Association Study of Gene Polymorphisms With Cardiac Performance
Observational Association Study of G Protein Polymorphisms With Cardiac Performance in Coronary Artery Disease Patients Undergoing Coronary Artery Bypass Grafting
1 other identifier
observational
500
1 country
1
Brief Summary
The purpose of this study is to determine whether polymorphisms in G protein subunits, namely Galphas and Galphaq, are associated with altered cardiac performance in heart failure patients.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started May 2008
Typical duration for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
May 1, 2008
CompletedFirst Submitted
Initial submission to the registry
August 4, 2008
CompletedFirst Posted
Study publicly available on registry
August 8, 2008
CompletedPrimary Completion
Last participant's last visit for primary outcome
January 1, 2011
CompletedStudy Completion
Last participant's last visit for all outcomes
June 1, 2011
CompletedAugust 8, 2008
August 1, 2008
2.7 years
August 4, 2008
August 4, 2008
Conditions
Outcome Measures
Primary Outcomes (1)
genotype dependent change of hemodynamic variables
one day
Secondary Outcomes (1)
all cause mortality
60 days
Eligibility Criteria
Patients with coronary artery disease scheduled for coronary artery bypass grafting in the university hospital
You may qualify if:
- clinical diagnosis of coronary artery disease
- patients scheduled for coronary artery bypass grafting
You may not qualify if:
- emergency operation
- combined vitium
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
University Hospital
Essen, North Rhine-Westphalia, 45147, Germany
Biospecimen
whole blood
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- STUDY DIRECTOR
Jürgen Peters, MD
University Hospital, Essen
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
August 4, 2008
First Posted
August 8, 2008
Study Start
May 1, 2008
Primary Completion
January 1, 2011
Study Completion
June 1, 2011
Last Updated
August 8, 2008
Record last verified: 2008-08