NCT00725894

Brief Summary

The purpose of this multi-center prospective clinical outcomes study is to determine validity and safety of the pediatric locking nail for femoral fracture management in children with open physes.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
33

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Nov 2007

Longer than P75 for all trials

Geographic Reach
1 country

3 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2007

Completed
9 months until next milestone

First Submitted

Initial submission to the registry

July 29, 2008

Completed
2 days until next milestone

First Posted

Study publicly available on registry

July 31, 2008

Completed
4.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2013

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2013

Completed
Last Updated

June 21, 2017

Status Verified

June 1, 2017

Enrollment Period

5.5 years

First QC Date

July 29, 2008

Last Update Submit

June 19, 2017

Conditions

Outcome Measures

Primary Outcomes (1)

  • limb alignment

    48 months

Secondary Outcomes (1)

  • length of healing, weight-bearing time (time to full weight bearing), and length of hospital stay and absence of complications

    48 Months

Study Arms (1)

1

The Pediatric Locking Nail was designed to provide stable sub-rigid fixation of femoral fractures in children

Device: Pediatric Locking Nail

Interventions

The nail is pre contoured with a nine-degree anterior bow and is universal for right and left femoral.

1

Eligibility Criteria

Age8 Years - 16 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)
Sampling MethodNon-Probability Sample
Study Population

Pediatric femoral fractures in patients 8-16 years of age where a nail is preferred

You may qualify if:

  • Subject, representative willing to sign informed consent.
  • Ability and willingness of the subject to follow postoperative care instructions until healing is complete
  • Subject age must be between 8-16 inclusive.
  • Subjects with a minimal canal diameter of 9mm or greater
  • And any of the following fracture types
  • Non-comminuted and comminuted mid-shaft fractures
  • Distal third fractures 4 cm above the distal physis
  • Fractures that are open or closed
  • Subtrochanteric fractures

You may not qualify if:

  • A subject has a bone or soft tissue infection.
  • Subject has a systemic infection.
  • Subject has a distal (supracondylar) fracture.
  • Subject with pathological bone (osteogenesis imperfecta and other conditions resulting in abnormal bone quality).
  • Subjects with mental or neurological condition who are unwilling or incapable of following postoperative care instructions.
  • Subject with conditions including blood supply limitation, and insufficient quantity or quality of bone.
  • Foreign body sensitivity, where material sensitivity is suspected, testing is to be completed prior to implantation of device if at all practical or the subject should be excluded.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

Phoenix Childrens Hospital

Phoenix, Arizona, 85016, United States

Location

Arnold Palmer Hospital for Children/OH Pediatric Orthopedics Clinic

Orlando, Florida, 32806, United States

Location

Orthopedic Clinical Research

Charlotte, North Carolina, 28204, United States

Location

MeSH Terms

Conditions

Femoral Fractures

Condition Hierarchy (Ancestors)

Fractures, BoneWounds and InjuriesLeg Injuries

Study Officials

  • Russell Schenck, PhD

    Zimmer Biomet

    STUDY DIRECTOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 29, 2008

First Posted

July 31, 2008

Study Start

November 1, 2007

Primary Completion

May 1, 2013

Study Completion

November 1, 2013

Last Updated

June 21, 2017

Record last verified: 2017-06

Locations