Acute Stroke Program of Interventions Addressing Racial and Ethnic Disparities

NCT00724555 | Completed

• 3 other identifiers: U54NS057405_ASPIRE2007-439U54NS057405
• Study Type: observational
• Target: 2,005
• Locations: 1 country
• Sites: 8

Brief Summary

The purpose of this study is to increase treatment of acute stroke with tissue plasminogen activator (tPA) across the District of Columbia. This study, however, will not evaluate tPA as an intervention.

Conditions

Stroke

Keywords

stroke; tissue plasminogen activator; tPA

Outcome Measures

Primary Outcomes (1)

• The proportion of people with ischemic stroke appropriately treated with IV tPA.

  4 years

Secondary Outcomes (1)

• Qualitative data collected from the community will identify baseline levels of knowledge, attitudes, and perceived and encountered barriers to acute stroke treatment.

  1 year

Study Arms (1)

1

Adults living in DC neighborhoods with high proportions of underserved adults. The age of the cohort members will reflect the age of DC residents who suffer most from stroke.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Adult residents of the District of Columbia

You may qualify if:

• diagnosis of acute ischemic stroke
• over the age of 18

Sponsors & Collaborators

• Georgetown University: lead
• Medstar Health Research Institute: collaborator
• Howard University: collaborator
• George Washington University: collaborator
• University of Michigan: collaborator
• University of Wisconsin, Madison: collaborator
• Johns Hopkins University: collaborator
• University of Alabama at Birmingham: collaborator
• MedStar Good Samaritan Hospital: collaborator
• Union Memorial Hospital: collaborator

Study Sites (8)

Georgetown University, ASPIRE Coordinating Center

Washington D.C., District of Columbia, 20007, United States

Location

Washington Hospital Center

Washington D.C., District of Columbia, 20010, United States

Location

Sibley Memorial Hospital

Washington D.C., District of Columbia, 20016, United States

Location

Providence Hospital

Washington D.C., District of Columbia, 20017, United States

Location

United Medical Center (formerly known as Greater Southeast Community Hospital)

Washington D.C., District of Columbia, 20032, United States

Location

George Washington University Hospital

Washington D.C., District of Columbia, 20037, United States

Location

Howard University Hospital

Washington D.C., District of Columbia, 20060, United States

Location

Columbia University Medical Center

New York, New York, 10032, United States

Location

Related Publications (1)

• Boden-Albala B, Edwards DF, St Clair S, Wing JJ, Fernandez S, Gibbons MC, Hsia AW, Morgenstern LB, Kidwell CS. Methodology for a community-based stroke preparedness intervention: the Acute Stroke Program of Interventions Addressing Racial and Ethnic Disparities Study. Stroke. 2014 Jul;45(7):2047-52. doi: 10.1161/STROKEAHA.113.003502. Epub 2014 May 15.

  PMID: 24876243 DERIVED

MeSH Terms

Conditions

Stroke

Condition Hierarchy (Ancestors)

Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases

Study Officials

• Chelsea Kidwell, MD

  Georgetown University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: ECOLOGIC OR COMMUNITY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor of Neurology and Medical Director, Georgetown University Stroke Center

Study Record Dates

• First Submitted: July 28, 2008
• First Posted: July 29, 2008
• Study Start: February 1, 2008
• Primary Completion: January 1, 2013
• Study Completion: January 1, 2013
• Last Updated: January 31, 2014

Record last verified: 2014-01

Locations

US (8)