NCT00724217

Brief Summary

To determine the effects of a commercially available dietary modification plus nutritional supplement regimen, the Standard Process 21 day Purification Program (SPPP), on serum lipids, C-reactive protein (CRP), homocysteine, body mass index (BMI), body weight, blood pressure, and heart rate variability (HRV) in normal weight (BMI \< 26) and overweight (BMI 26 or above) participants who have total cholesterol levels over 180.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
40

participants targeted

Target at P50-P75 for phase_1

Timeline
Completed

Started Jul 2008

Shorter than P25 for phase_1

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2008

Completed
24 days until next milestone

First Submitted

Initial submission to the registry

July 25, 2008

Completed
4 days until next milestone

First Posted

Study publicly available on registry

July 29, 2008

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2009

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2009

Completed
Last Updated

July 29, 2008

Status Verified

July 1, 2008

Enrollment Period

8 months

First QC Date

July 25, 2008

Last Update Submit

July 28, 2008

Conditions

Outcome Measures

Primary Outcomes (1)

  • Serum lipids

    Before and 3 weeks after starting SPPP (dietary modification + whole food supplements)

Secondary Outcomes (1)

  • Total cholesterol, LDL cholesterol, HDL cholesterol, triglycerides, homocysteine, C-reactive protein, blood pressure, heart rate variability, body mass index

    Before and 3 weeks after starting SPPP (dietary modification + whole food supplements)

Study Arms (2)

Normal weight

EXPERIMENTAL

BMI \< 26

Other: Standard Process 21 Day Purification Program (SPPP)

Overweight

EXPERIMENTAL

BMI \>= 26

Other: Standard Process 21 Day Purification Program (SPPP)

Interventions

The Standard Process 21 Day Purification Program (SPPP) consists of a controlled food intake regimen of mostly fruit and vegetables with restricted calories, protein and fats plus daily use of herbal and whole food based supplements.

Normal weight

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • The two experimental groups will be 1. normal weight participants (BMI \< 26) and 2. overweight participants (BMI 26 or above).
  • All participants will have total cholesterol levels over 180.
  • Both male and female subjects between the ages of 18-65 will be included in the study.

You may not qualify if:

  • Individuals with diabetes, heart, kidney, thyroid disorders, neurological diseases, and chronic disease will be excluded from the study.
  • Female subjects who are pregnant or breast feeding and those using blood lipid modifying medications and/or supplements drugs and/or hypertension will be excluded from study.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Logan College of Chiropractic

Chesterfield, Missouri, 63017, United States

RECRUITING

MeSH Terms

Conditions

Hyperlipidemias

Condition Hierarchy (Ancestors)

DyslipidemiasLipid Metabolism DisordersMetabolic DiseasesNutritional and Metabolic Diseases

Central Study Contacts

Rodger Tepe, PhD

CONTACT

John Zhang, MD, PhD

CONTACT

Study Design

Study Type
interventional
Phase
phase 1
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER

Study Record Dates

First Submitted

July 25, 2008

First Posted

July 29, 2008

Study Start

July 1, 2008

Primary Completion

March 1, 2009

Study Completion

March 1, 2009

Last Updated

July 29, 2008

Record last verified: 2008-07

Locations