NCT00719940

Brief Summary

Test of hypothesis that in contrast to non-treatment tinnitus specific cognitive behavioral therapy intervention procedures that are manualized and structured within the disease management program TCP are effective.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
286

participants targeted

Target at P75+ for phase_4

Timeline
Completed

Started Oct 2000

Longer than P75 for phase_4

Geographic Reach
1 country

4 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2000

Completed
4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2004

Completed
2.1 years until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2006

Completed
1.6 years until next milestone

First Submitted

Initial submission to the registry

June 16, 2008

Completed
1 month until next milestone

First Posted

Study publicly available on registry

July 22, 2008

Completed
Last Updated

July 22, 2008

Status Verified

June 1, 2008

Enrollment Period

4 years

First QC Date

June 16, 2008

Last Update Submit

July 18, 2008

Conditions

Keywords

tinnitus, cognitive behavioral therapy, CBT

Outcome Measures

Primary Outcomes (1)

  • Validated tinnitus questionaire (TF Goebel and Hiller 1992); validated tinnitus change rating scale (TC, Zenner and de Maddalena 2005)

    Last session

Secondary Outcomes (1)

  • Tinnitus loudness (TL), validated 6-point numeric verbal rating scale; tinnitus annoyance (TA), validated 8-point numeric verbal rating scale

    last therapy session

Study Arms (2)

1

EXPERIMENTAL

Cognitive behavioral therapy

Behavioral: Cognitive behavioral therapy

2

PLACEBO COMPARATOR

Waiting group

Other: Waiting group

Interventions

1-15 individual sessions of 50-60 min. to apply 1-15 manualized tinnitus specific cognitive behavioral therapy interventions structured by the tinnitus care disease management program

Also known as: tinnitus care program
1

No intervention

Also known as: tinnitus care program
2

Eligibility Criteria

Age14 Years - 90 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Persistent and stable tinnitus of more than 11 weeks
  • Gap between audiometric tinnitus matching and subjective tinnitus loudness rating scale

You may not qualify if:

  • Psychiatric or neurological comorbidity
  • Tinnitus as concomitant symptom of an otherwise treatable disease
  • Drug treatment for tinnitus 24 hrs. prior or during therapy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (4)

Tinnitus Care Center

Aschaffenburg, 63739, Germany

Location

Tinnitus Care Center

Frankfurt, 60594, Germany

Location

Dept. ORL, University of Tuebingen

Tübingen, 72070, Germany

Location

Private Practice

Tübingen, 72070, Germany

Location

Related Publications (2)

  • Zenner HP, De Maddalena H. Validity and reliability study of three tinnitus self-assessment scales: loudness, annoyance and change. Acta Otolaryngol. 2005 Nov;125(11):1184-8. doi: 10.1080/00016480510012282.

  • Zenner HP, Vonthein R, Zenner B, Leuchtweis R, Plontke SK, Torka W, Pogge S, Birbaumer N. Standardized tinnitus-specific individual cognitive-behavioral therapy: a controlled outcome study with 286 tinnitus patients. Hear Res. 2013 Apr;298:117-25. doi: 10.1016/j.heares.2012.11.013. Epub 2012 Dec 31.

MeSH Terms

Conditions

TinnitusColor Vision Defects

Interventions

Cognitive Behavioral Therapy

Condition Hierarchy (Ancestors)

Hearing DisordersEar DiseasesOtorhinolaryngologic DiseasesSensation DisordersNeurologic ManifestationsNervous System DiseasesSigns and SymptomsPathological Conditions, Signs and SymptomsVision DisordersCone DystrophyEye Diseases, HereditaryEye Diseases

Intervention Hierarchy (Ancestors)

Behavior TherapyPsychotherapyBehavioral Disciplines and Activities

Study Officials

  • Hans P. Zenner, M.D.

    Universität Tübingen

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 4
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER

Study Record Dates

First Submitted

June 16, 2008

First Posted

July 22, 2008

Study Start

October 1, 2000

Primary Completion

October 1, 2004

Study Completion

November 1, 2006

Last Updated

July 22, 2008

Record last verified: 2008-06

Locations