NCT00718406

Brief Summary

The primary aim was to evaluate the relief of chest pain during the first 30 minutes among patients who received metoprolol alone as compared with metoprolol plus morphine

Trial Health

80
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 16, 2008

Completed
2 days until next milestone

First Posted

Study publicly available on registry

July 18, 2008

Completed
Last Updated

July 18, 2008

Status Verified

August 1, 2002

First QC Date

July 16, 2008

Last Update Submit

July 16, 2008

Conditions

Acute Coronary Syndromes

Keywords

Acute coronary syndromeChest painBetablockersMorphinePrehospital phase

Study Arms (2)

A

ACTIVE COMPARATOR

A=metoprolol

Drug: Metoprolol

B

ACTIVE COMPARATOR

B=metoprolol plus morphine

Drug: metoprolol plus morphine

Interventions

MetoprololDRUG
A
metoprolol plus morphineDRUG
B

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Acute chest pain
  • ECG-signs indicating myocardial ischemia

You may not qualify if:

  • Heart rate \< 60 beats/min
  • Systolic blood pressure \< 110 mmHg
  • High degree AV-block
  • Signs of obstructive pulmonary disease
  • Signs of pulmonary oedema
  • Unwillingness
  • Participation in other studies
  • Long delay between arrival of ambulance and randomisation

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Medical Institution, Dept of Molecular and Clinical Medicine, Sahlgrenska University Hospital

Gothenburg, SE-413 45, Sweden

Location

MeSH Terms

Conditions

Acute Coronary SyndromeChest Pain

Interventions

MetoprololMorphine

Condition Hierarchy (Ancestors)

Myocardial IschemiaHeart DiseasesCardiovascular DiseasesVascular DiseasesPainNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

PhenoxypropanolaminesPropanolaminesAmino AlcoholsAlcoholsOrganic ChemicalsPropanolsAminesMorphine DerivativesMorphinansOpiate AlkaloidsAlkaloidsHeterocyclic CompoundsHeterocyclic Compounds, Bridged-RingHeterocyclic Compounds, 4 or More RingsHeterocyclic Compounds, Fused-RingPhenanthrenesPolycyclic Aromatic HydrocarbonsPolycyclic Compounds

Study Design

Study Type
interventional
Phase
phase 4
Sponsor Type
OTHER

Study Record Dates

First Submitted

July 16, 2008

First Posted

July 18, 2008

Last Updated

July 18, 2008

Record last verified: 2002-08

Locations

SE(1)