European Quality Improvement Programme for Acute Coronary Syndromes
EQUIP-ACS
Improving the Management of Non-ST Elevation Acute Coronary Syndrome: Systematic Evaluation of a Quality Improvement Programme
1 other identifier
interventional
3,500
5 countries
37
Brief Summary
The main hypothesis to be tested is that the use of a quality improvement programme will lead to measurable improvements in the management of care and use of evidence based treatments for patients presenting to hospital with non-ST elevation acute coronary syndromes.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Aug 2007
37 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
August 1, 2007
CompletedFirst Submitted
Initial submission to the registry
July 11, 2008
CompletedFirst Posted
Study publicly available on registry
July 16, 2008
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2008
CompletedStudy Completion
Last participant's last visit for all outcomes
February 1, 2009
CompletedJuly 16, 2008
July 1, 2008
1.3 years
July 11, 2008
July 15, 2008
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Composite of 7 outcome measures to assess aggregate potential for improvement in care using the QI programme:1:risk stratification within 24 hrs, 2:early coronary angiography, 3:anticoagulation, 4:beta-blockers, 5:statins, 6:ACE-inhibitors, 7:Clopidogrel
10 months
Secondary Outcomes (3)
Clinical outcomes at discharge including death and myocardial infarction
10 months
Estimated costs of care for patients
10 months
Estimated costs and economic evaluation of potential cost-effectiveness of QI programme
10 months
Study Arms (2)
QI
ACTIVE COMPARATORQuality Improvement Centres
Non-QI
NO INTERVENTIONNo Quality Improvement Programme
Interventions
Eligibility Criteria
You may qualify if:
- Patients with a good clinical history of ACS and at least one of the following:
- New or transient ST or T wave changes on the ECG consistent with acute myocardial ischaemia
- Elevation of troponin or other cardiac markers to levels indicative of myocardial necrosis according to local laboratory values
You may not qualify if:
- Evidence of persistent ST elevation on the ECG
- Use of early reperfusion therapy
- Patients \>80 years
- Patients transferred from another hospital
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Royal Brompton & Harefield NHS Foundation Trustlead
- Uppsala Universitycollaborator
- GlaxoSmithKlinecollaborator
Study Sites (37)
Centre Hospitalier de la region d'Annecy
Annecy, France
Centre Hospitalier de Chambery
Chambéry, France
Cardiology dept. B, CHU Hopital G. Montpied
Clermont-Ferrand, France
CHU de Grenoble
Grenoble, France
Centre Hospitalier de Riom Guy Thomas
Riom, France
Hopitaux Drome Nord de Romans-sur-Isere
Romans-sur-Isère, France
Centre Hospitalier d'Ussel
Ussel, France
Centre Hospitalier Pierre Bazin
Voiron, France
Ospedale M. Bufalini
Cesena, Italy
Ospedale Morgagni-Pierantoni
Forlì, Italy
Ospedale di Livorno
Livorno, Italy
Ospedale Generale Provinciale di Macerata
Macerata, Italy
Ospedale Civile di Mirano
Mirano, Italy
Szpital w Ciechanowie
Ciechanów, Poland
Szpital Zachodni
Grodzisk Mazowiecki, Poland
Szpital w Grojcu
Grójec, Poland
Swietofrzyskie Centrum Chorob Serca
Kielce, Poland
Szpital w Plocku
Płock, Poland
Radomski Szpital Specjalistyczny
Radom, Poland
Szpital Specjalistyczny SPZOZ w Radom
Radom, Poland
Szpital w Siedlcach
Siedlce, Poland
SP CSK- Medical University of Warsaw
Warsaw, Poland
Szpital we Wloclawku
Włocławek, Poland
Hospital Universitario Germans Trias
Badalona, Spain
Hospital del Mar
Barcelona, Spain
Hospital Universitario Vall d'Hebron
Barcelona, Spain
Hospital Josep Trueta
Girona, Spain
Hospital Universitario Joan XXIII
Tarragona, Spain
Hospital de Terrassa
Terrassa-Barcelona, Spain
Hospital de Tortosa Virgen de la Cinta
Tortosa, Spain
Antrim Area Hospital
Antrim, United Kingdom
Barnet General Hospital
Barnet, United Kingdom
Basildon Hospital
Essex, United Kingdom
Warwick Hospital
Warwick, United Kingdom
Royal Albert Edward Infirmary
Wigan, United Kingdom
Yeovil District Hospital
Yeovil, United Kingdom
York District Hospital
York, United Kingdom
Related Publications (2)
Flather MD, Babalis D, Booth J, Bardaji A, Machecourt J, Opolski G, Ottani F, Bueno H, Banya W, Brady AR, Bojestig M, Lindahl B. Cluster-randomized trial to evaluate the effects of a quality improvement program on management of non-ST-elevation acute coronary syndromes: The European Quality Improvement Programme for Acute Coronary Syndromes (EQUIP-ACS). Am Heart J. 2011 Oct;162(4):700-707.e1. doi: 10.1016/j.ahj.2011.07.027.
PMID: 21982663DERIVEDFlather MD, Booth J, Babalis D, Bueno H, Steg PG, Opolski G, Ottani F, Machecourt J, Bardaji A, Bojestig M, Brady AR, Lindahl B. Improving the management of non-ST elevation acute coronary syndromes: systematic evaluation of a quality improvement programme European QUality Improvement Programme for Acute Coronary Syndrome: the EQUIP-ACS project protocol and design. Trials. 2010 Jan 14;11:5. doi: 10.1186/1745-6215-11-5.
PMID: 20074348DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- HEALTH SERVICES RESEARCH
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
July 11, 2008
First Posted
July 16, 2008
Study Start
August 1, 2007
Primary Completion
December 1, 2008
Study Completion
February 1, 2009
Last Updated
July 16, 2008
Record last verified: 2008-07