NCT00712608

Brief Summary

A study to evaluate the growth and development of term infants fed either a marketed cow's milk formula, or an experimental cow's milk formula with prebiotics + a different calcium source + a different level of fatty acids and fat, or an experimental cow's milk formula with prebiotic + a different calcium source + a different level of fatty acids and fat

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
399

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Aug 2008

Geographic Reach
1 country

22 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 8, 2008

Completed
2 days until next milestone

First Posted

Study publicly available on registry

July 10, 2008

Completed
22 days until next milestone

Study Start

First participant enrolled

August 1, 2008

Completed
1.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2009

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2009

Completed
Last Updated

January 28, 2010

Status Verified

April 1, 2009

Enrollment Period

1.2 years

First QC Date

July 8, 2008

Last Update Submit

January 26, 2010

Conditions

Keywords

TermInfantFormula

Outcome Measures

Primary Outcomes (1)

  • Rate of weight gain

    106 days

Secondary Outcomes (1)

  • length and head circumference

    106 days

Study Arms (3)

1

ACTIVE COMPARATOR

Marketed cow's milk-based formula

Other: Infant formula

2

EXPERIMENTAL

Cow's milk based formula with prebiotics, different level of fatty acids and fat and a different calcium source

Other: Infant formula

3

EXPERIMENTAL

Cow's milk based formula with prebiotic, different level of fatty acids and fat and a different calcium source

Other: Cow's milk infant formula

Interventions

Marketed cow's milk base infant formula 20 kcal/oz

Also known as: Similar to Enfamil LIPIL with iron
1

Cow's milk based formula with prebiotics, different level of fatty acids and fat and a different calcium source

Also known as: No other similar brand names; experimental product
3

Eligibility Criteria

Age12 Days - 16 Days
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)

You may qualify if:

  • Term infant
  • days of age
  • weeks GA

You may not qualify if:

  • History of chronic disease, congenital malformation
  • Feeding difficulties or formula intolerance
  • LGA

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (22)

Birmingham Pediatric Group

Birmingham, Alabama, 35205, United States

Location

Alabama Clinical Therapeutics

Dothan, Alabama, 36305, United States

Location

Central Arkansas Pediatric Clinic

Benton, Arkansas, 72019, United States

Location

Medical Associates

Fayetteville, Arkansas, 72703, United States

Location

Arkansas Children's Hospital Research Institute

Little Rock, Arkansas, 72202, United States

Location

Arkansas Pediatric Clinic

Little Rock, Arkansas, 72205, United States

Location

Norwich Pediatric Group, PC

Norwich, Connecticut, 06360, United States

Location

Palm Beach Clinical Investigation, LLC

West Palm Beach, Florida, 33407, United States

Location

Welborn Clinic Research

Newburgh, Indiana, 47630, United States

Location

Woburn Pediatric Associates Research Department

Woburn, Massachusetts, 01801, United States

Location

Southwestern Medical Clinic, PC

Niles, Michigan, 49120, United States

Location

Southwestern Medical Clinic, PC

Stevensville, Michigan, 49127, United States

Location

Aspen Medical Group

Saint Paul, Minnesota, 55108, United States

Location

The Center for Human Nutrition

Omaha, Nebraska, 68105, United States

Location

Odyssey Research

Minot, North Dakota, 58701, United States

Location

Red Lion Pediatrics

Philadelphia, Pennsylvania, 19114, United States

Location

Primary Physicians Research, Inc

Pittsburgh, Pennsylvania, 15241, United States

Location

Holston Medical Group, MeadowView Lane

Kingsport, Tennessee, 37660, United States

Location

Holston Medical Group

Kingsport, Tennessee, 37660, United States

Location

Retina Foundation of the Southwest

Dallas, Texas, 75231, United States

Location

DCOL Center for Clinical Research

Longview, Texas, 75605, United States

Location

Texas Tech University Health Sciences Center

Lubbock, Texas, 79430, United States

Location

Related Publications (1)

  • Ashley C, Johnston WH, Harris CL, Stolz SI, Wampler JL, Berseth CL. Growth and tolerance of infants fed formula supplemented with polydextrose (PDX) and/or galactooligosaccharides (GOS): double-blind, randomized, controlled trial. Nutr J. 2012 Jun 7;11:38. doi: 10.1186/1475-2891-11-38.

MeSH Terms

Interventions

Infant FormulaIron

Intervention Hierarchy (Ancestors)

Milk SubstitutesBeveragesDiet, Food, and NutritionPhysiological PhenomenaFood, FormulatedFoods, SpecializedFoodInfant FoodFood and BeveragesMetals, HeavyElementsInorganic ChemicalsTransition ElementsMetals

Study Officials

  • Carol L Berseth, MD

    Mead Johnson & Company

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
QUADRUPLE
Who Masked
PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
Intervention Model
PARALLEL
Sponsor Type
INDUSTRY

Study Record Dates

First Submitted

July 8, 2008

First Posted

July 10, 2008

Study Start

August 1, 2008

Primary Completion

October 1, 2009

Study Completion

October 1, 2009

Last Updated

January 28, 2010

Record last verified: 2009-04

Locations