NCT00707005

Brief Summary

The purpose of this study is to determine the in vitro antibiotic susceptibility patterns of conjunctival bacterial flora isolated preoperatively from patients undergoing refractive surgery.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
105

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Jun 2008

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2008

Completed
25 days until next milestone

First Submitted

Initial submission to the registry

June 26, 2008

Completed
4 days until next milestone

First Posted

Study publicly available on registry

June 30, 2008

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2008

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2008

Completed
Last Updated

November 1, 2016

Status Verified

October 1, 2016

Enrollment Period

2 months

First QC Date

June 26, 2008

Last Update Submit

October 30, 2016

Conditions

Bacterial Keratitis

Keywords

antibiotic susceptibilitybacterial florafluoroquinoloneLASIKrefractive surgery

Outcome Measures

Primary Outcomes (1)

  • Minimum inhibitory concentrations of commonly used antibiotics are determined using an E-test.

    3 months

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Myopia patients scheduled for refractive surgery

You may qualify if:

  • Myopia patients scheduled for refractive surgery

You may not qualify if:

  • Active keratitis
  • Current treatment of antibiotics (systemic or topical)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Yonsei University Health System

Seoul, Kyoungkido, 120-752, South Korea

Location

Related Publications (1)

  • Mino de Kaspar H, Koss MJ, He L, Blumenkranz MS, Ta CN. Antibiotic susceptibility of preoperative normal conjunctival bacteria. Am J Ophthalmol. 2005 Apr;139(4):730-3. doi: 10.1016/j.ajo.2004.10.007.

    PMID: 15808182BACKGROUND

Biospecimen

Retention: SAMPLES WITHOUT DNA

Conjunctival swab samples

Study Officials

  • Kyoung Yul Seo, M.D.

    Yonsei University

    STUDY CHAIR

Study Design

Study Type
observational
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER

Study Record Dates

First Submitted

June 26, 2008

First Posted

June 30, 2008

Study Start

June 1, 2008

Primary Completion

August 1, 2008

Study Completion

August 1, 2008

Last Updated

November 1, 2016

Record last verified: 2016-10

Locations

KR(1)