NCT00702429

Brief Summary

Our design is to test in hospital practice a selection of immune parameters that could assess the pathophysiology and progression of periodontal lesions.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
23

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Aug 2008

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 18, 2008

Completed
2 days until next milestone

First Posted

Study publicly available on registry

June 20, 2008

Completed
1 month until next milestone

Study Start

First participant enrolled

August 1, 2008

Completed
1.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2010

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2010

Completed
Last Updated

August 28, 2014

Status Verified

August 1, 2014

Enrollment Period

1.9 years

First QC Date

June 18, 2008

Last Update Submit

August 27, 2014

Conditions

Periodontal Disease

Outcome Measures

Primary Outcomes (1)

  • Percentage of positive cells and intensity of expression for the molecules of surface studied there cytometric in stream

    24 months

Secondary Outcomes (2)

  • Rate of secretion of cytokines and the other substances

    24 months

  • Detection and quantification of ARN messengers

    24 months

Study Arms (2)

1

EXPERIMENTAL

Patients achieve of parodontopathies

Other: Blood sampling

2

PLACEBO COMPARATOR

Patients without parodontales diseases

Other: Blood sampling

Interventions

Blood samplingOTHER

Analysis of the PNN, analysis of the monocytes

1

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Persons appearing spontaneously at the consultation of parodontologie for parodontale disease,
  • persons agreeing to undergo a sampling of blood intended for the search

You may not qualify if:

  • Presence of a chronic or pointed pathology,
  • an age 18-year-old subordinate or 65-year-old superior,
  • pregnant women,

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Hopital de la Conception- Laboratoire d'Immunologie

Marseille, 13274, France

Location

MeSH Terms

Conditions

Periodontal Diseases

Interventions

Blood Specimen Collection

Condition Hierarchy (Ancestors)

Mouth DiseasesStomatognathic Diseases

Intervention Hierarchy (Ancestors)

Specimen HandlingClinical Laboratory TechniquesDiagnostic Techniques and ProceduresDiagnosisPuncturesSurgical Procedures, OperativeInvestigative Techniques

Study Officials

  • Joana VITTE, MD

    Assistance Publique des Hôpitaux de Marseille

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 18, 2008

First Posted

June 20, 2008

Study Start

August 1, 2008

Primary Completion

July 1, 2010

Study Completion

July 1, 2010

Last Updated

August 28, 2014

Record last verified: 2014-08

Locations

FR(1)