NCT00701064

Brief Summary

The investigators are testing novel treatments for combat PTSD: bright light exposure and negation ion exposure.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
71

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Jan 2009

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 17, 2008

Completed
2 days until next milestone

First Posted

Study publicly available on registry

June 19, 2008

Completed
7 months until next milestone

Study Start

First participant enrolled

January 1, 2009

Completed
3.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 21, 2012

Completed
2.4 years until next milestone

Results Posted

Study results publicly available

April 29, 2015

Completed
4.3 years until next milestone

Study Completion

Last participant's last visit for all outcomes

September 2, 2019

Completed
Last Updated

September 24, 2019

Status Verified

September 1, 2019

Enrollment Period

3.9 years

First QC Date

June 17, 2008

Results QC Date

March 26, 2015

Last Update Submit

September 11, 2019

Conditions

Keywords

posttraumatic stress disorderphototherapyanxietydepressionsleepnegative ion generator

Outcome Measures

Primary Outcomes (2)

  • Clinical Assessed PTSD Scale (CAPS-2)

    The CAPS-2 is administered by a trained clinician. It is designed to assess changes in PTSD severity over time, the scale ranges from 0-136. Higher levels indicate greater severity of PTSD.

    Mean change from baseline to post-treatment (5-6 weeks later)

  • Clinical Global Impressions Scale (CGI)

    The CGI assesses baseline severity on a 7-point scale, and change on 7-point scale. (1=normal; 4=moderately ill; 7= among the most severely ill). Change: 1=very much improved, 2=much improved, 3=minimally improved, 4=no change, 5=minimally worse, 6=much worse, 7=very much worse

    Baseline severity to post-treatment (4 weeks later) Change

Secondary Outcomes (1)

  • Posttraumatic Stress Disorder Checklist (PCL-M)

    Baseline to following 4-week treatment

Study Arms (2)

Bright Light Exposure

EXPERIMENTAL

Bright Light (30 min/day)

Other: Bright Light Exposure

Negative Ion Generator

PLACEBO COMPARATOR

Negative Ion Generator (30 min/day)

Other: Negative Ion Generator

Interventions

Administered via bright light box

Bright Light Exposure

Administered via Negative Ion Generatore

Negative Ion Generator

Eligibility Criteria

Age18 Years - 60 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Veteran of Operation Iraqi Freedom or Operation Enduring Freedom with Posttraumatic Stress Disorder
  • receiving other treatment or stopped other treatment prior to study

You may not qualify if:

  • bipolar disorder
  • psychosis
  • alcohol/drug abuse

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Wm. Jennings Bryan Dorn VA Medical Center, Columbia, SC

Columbia, Arizona, 29209, United States

Location

MeSH Terms

Conditions

Stress Disorders, Post-TraumaticAnxiety DisordersDepression

Condition Hierarchy (Ancestors)

Stress Disorders, TraumaticTrauma and Stressor Related DisordersMental DisordersBehavioral SymptomsBehavior

Results Point of Contact

Title
Shawn Youngstedt
Organization
VA

Study Officials

  • Shawn D. Youngstedt, PhD

    Wm. Jennings Bryan Dorn VA Medical Center, Columbia, SC

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
FED
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 17, 2008

First Posted

June 19, 2008

Study Start

January 1, 2009

Primary Completion

November 21, 2012

Study Completion

September 2, 2019

Last Updated

September 24, 2019

Results First Posted

April 29, 2015

Record last verified: 2019-09

Data Sharing

IPD Sharing
Will not share

Locations