NCT00693628

Brief Summary

We expect subjects in the interventional groups, who wear shrinkers, to heal more quickly than control subjects who wear no shrinkers. We also expect them to experience greater reduction in residual limb volume during the early stages of postoperative care leading up to prosthetic fitting, fewer healing complications, reduced time to the prosthetic fitting, increased time to the first prosthetic socket replacement, and fewer socket replacements by the end of the "transition to stable phase".

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
4

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Mar 2007

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
terminated

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2007

Completed
10 months until next milestone

First Submitted

Initial submission to the registry

December 20, 2007

Completed
6 months until next milestone

First Posted

Study publicly available on registry

June 9, 2008

Completed
3.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2012

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2012

Completed
5.3 years until next milestone

Results Posted

Study results publicly available

May 3, 2017

Completed
Last Updated

June 5, 2017

Status Verified

May 1, 2017

Enrollment Period

4.8 years

First QC Date

December 20, 2007

Results QC Date

March 22, 2017

Last Update Submit

May 3, 2017

Conditions

Keywords

volumehealingshrinkertranstibial amputationindividuals who have undergone transtibial amputation

Outcome Measures

Primary Outcomes (1)

  • Reduction in Time to Healing

    time to healing in each group

    1 year

Study Arms (3)

Shrinker

ACTIVE COMPARATOR

Patients receive 20-30 mmHg compression shrinker, an elastic compression garment that is worn on the residual limb and is used to reduce edema and promote healing.

Device: compression shrinker

No Shrinker

NO INTERVENTION

Control group - participants will not receive an intervention (compression shrinker).

Shrinker 2

ACTIVE COMPARATOR

Patients receive 30-40 mmHg compression shrinker, an elastic compression garment that is worn on the residual limb and is used to reduce edema and promote healing.

Device: compression shrinker

Interventions

Two levels of compression: 20-30 mmHg or 30-40 mmHg shrinker

Also known as: Juzo® Compression Therapy Garment
ShrinkerShrinker 2

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Recently undergone primary transtibial amputation
  • Patients between ages of 18 and 100 years of age

You may not qualify if:

  • Undergone previous amputations above the Symes level

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Oklahoma Health Sciences Center, O'Donoghue Orthotics & Prosthetics Clinic

Oklahoma City, Oklahoma, 73104, United States

Location

Limitations and Caveats

Early termination of the study due to poor enrollment numbers, (only 4 subjects were enrolled). No analysis was performed due to insufficient data to assess outcome measures.

Results Point of Contact

Title
Jonathan Day
Organization
Department of Orthopedic Surgery & Rehabilitation, Orthotics and Prosthetics Division

Study Officials

  • Jonathan Day, BSPO

    University of Oklahoma Health Sciences Center Department of Orthopedic Surgery & Rehabilitation, Division of Orthotics & Prosthetics

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 20, 2007

First Posted

June 9, 2008

Study Start

March 1, 2007

Primary Completion

January 1, 2012

Study Completion

January 1, 2012

Last Updated

June 5, 2017

Results First Posted

May 3, 2017

Record last verified: 2017-05

Data Sharing

IPD Sharing
Will not share

Locations