Force Enhancement of Musculus Quadriceps Femoris During and After Excentric Muscle Activity in Vivo

NCT00690547 | Unknown

• 1 other identifier: DFG27112007
• Study Type: observational
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

Force enhancement (FE) describes the phenomenon of strength potentialization of a muscle cell or the complete muscle during and after active extension compared to the strength of an isometric contraction with same muscle length. The underlying physiological mechanism of this phenomenon is not completely known today. In vitro trials indicate that the interaction of an active and a passive component on the cellular level are responsible for the higher strength measurements. So far FE could be shown in vitro and in vivo on muscle fibers and small human muscles. Further research is needed for verification of the existence of FE in voluntary motor activity in everyday life. In order to approach this objective the investigators will scrutinize the functionality of the deliberately activated musculus (m) quadriceps femoris during and after active extension on the basis of in vivo studies.

Conditions

Muscle Quadriceps Femoris; Healthy

Keywords

Functionality; Deliberately; Activated; Quadriceps; Femoris; During; After; Active; Extension

Outcome Measures

Primary Outcomes (1)

• Identification of a potential Force enhancement by complex muscle activity with a high relevance for everyday life, for example more agile leg stretching (knee bend).

  12 months

Secondary Outcomes (3)

• Evidence of existence of the force enhancement by deliberately activated, great human muscle by sub-maximal activation

  12 months

• Correlation between typ of muscle fiber and force enhancement in vivo

  12 months

• Analysis of the alternation of length of the muscle fiber during and after excentric extension for the differentiated explanation of in vivo mechanism excentric and post-excentric strength

  12 months

Study Arms (1)

Test Group

Other: muscle activation

Interventions

muscle activation OTHER

activation of the muscle quadriceps femoris

Test Group

Eligibility Criteria

• Age: 20 Years - 40 Years
• Sex: male
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

males without previous muscular or neurophysiological diseases at an age between 20 and 40 years

You may qualify if:

• Males without previous muscular or neurophysiological diseases
• Age between 20 and 40 years

You may not qualify if:

• Previous muscular or neurophysiological diseases

Sponsors & Collaborators

• German Research Foundation: lead

Study Sites (1)

Technical University of Munich, Department of Biomechanics in Sports

Munich, 80809, Germany

Location

MeSH Terms

Conditions

Motor Activity

Condition Hierarchy (Ancestors)

Behavior

Study Officials

• Ansgar Schmirtz, Prof. Dr.

  Technical University of Munich, Department of Biomechanics in Sports

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: May 30, 2008
• First Posted: June 4, 2008
• Study Start: October 1, 2008
• Primary Completion: October 1, 2010
• Study Completion: October 1, 2010
• Last Updated: November 30, 2009

Record last verified: 2009-11

Locations

DE (1)