A Multi-Center Study of Rehabilitation to Stable Chronic Obstructive Pulmonary Disease (COPD) Patients

NCT00686660 | Unknown DMC

• 1 other identifier: COPD rehabilitation CYH 2007
• Study Type: interventional
• Target: 300
• Locations: 1 country
• Sites: 1

Brief Summary

This is a multi-center prospective follow-up study.

• to choose the stable COPD patients in community
• to compare different modes of exercise (cycling and walking)
• to compare the effect of different exercises on the quality of life,exercise endurance,dyspnea and depression

Conditions

COPD; Inflammation

Keywords

copd; rehabilitation; quality of life; inflammation

Outcome Measures

Primary Outcomes (1)

• quality of life, dyspnea score, exercise endurance, depression,markers of inflammation (CRP, TNF, IL-8)

  two years

Study Arms (4)

1

EXPERIMENTAL

C-W G: in training period, patients do cycling on cycle ergometry at hospital. in non-training period, patients walk at community.

Behavioral: cycling, walking

2

OTHER

C-nonW G: in training period, patients do cycling at cycle ergometry at hospital, in non-training period, patients don't walk at community.

Behavioral: cycling, non-walking

3

EXPERIMENTAL

W-W G: in training period, patients do walking along 60 meters place at hospital, in non-training period, patients do walking in community

Behavioral: walking, walking

4

OTHER

W-nonW G: in training period, patients do walking along 60 meter place, in non-training period,patients don't walk at community.

Behavioral: walking, non-walking

Interventions

cycling, walking BEHAVIORAL

In training period, patients do cycling on cycle ergometry. two times per week, 8 weeks per training period, two training period per year, two years. In non-training period, patients do walking at community. four days per week,18 weeks per non-training period, two non-training period per year, two years.

Also known as: no.

1

cycling, non-walking BEHAVIORAL

In training period, patients do cycling. two times a week, 8 weeks per training period, two training period per year, two years. In non-training period, patients don't receive walk training.

Also known as: no.

2

walking, walking BEHAVIORAL

In training period, patients do walking at hospital, two times per week, 8 weeks per training period, two training period per year, two years. In non-training period, patients do walking at community, four days per week, 18 weeks per non-training period, two non-training period per year, two years.

Also known as: no.

3

walking, non-walking BEHAVIORAL

In training period, patients do walking at hospital, two times per week, 8 weeks per training period, two training period per year, two years. In non-training period, patients don't walking at community.

Also known as: no.

4

Eligibility Criteria

• Age: 40 Years - 75 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• according to GOLD, patients who are diagnosed as COPD, lung function at II or III grades (II:50%≤FEV1\<60%pre；III:30%≤FEV1\<50%pre）；
• ≤age≤75 years old；
• don't have acute exacerbation in the past one month；
• SpO2 \> 88% at rest；

You may not qualify if:

• diabetes,blood glucose don't control well;
• vascular diseases(vasculitis,deep venous thrombosis,varicose veins, etc);
• joint diseases which may affect activities;
• cerebrovascular diseases which may affect activities;
• unstable angina during the past 1 month of acute myocardial infarction in the past 6 months;
• severe arrhythmia;
• cardia insufficiency;
• hypertension which don't control well(systolic pressure\>160mmHg and/or diastolic pressure\> 100mmHg);
• chronic liver or renal insufficiency;
• cognitive handicap.

Sponsors & Collaborators

• Beijing Chao Yang Hospital: lead
• Beijing Tongren Hospital: collaborator
• Xuanwu Hospital, Beijing: collaborator
• Beijing Fuxing Hospital: collaborator
• Peking University First Hospital: collaborator
• Beijing Miner General Hospital: collaborator
• Guang'anmen Hospital of China Academy of Chinese Medical Sciences: collaborator
• Beijing Shuyi Hospital: collaborator
• Beijing Daxing Hospital: collaborator
• Beijing Huairou Hospital: collaborator

Study Sites (1)

Beijing Chaoyang Hospital

Beijing, Beijing Municipality, 100020, China

RECRUITING

MeSH Terms

Conditions

Pulmonary Disease, Chronic Obstructive; Inflammation

Interventions

Walking

Condition Hierarchy (Ancestors)

Lung Diseases, Obstructive; Lung Diseases; Respiratory Tract Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Locomotion; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena; Exercise; Motor Activity

Study Officials

• chen wang, phD

  Beijing Chao Yang Hospital

  PRINCIPAL INVESTIGATOR

Central Study Contacts

ting yang, phD

CONTACT

86-136-5138-0809; dryangting@yahoo.com.cn

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: May 27, 2008
• First Posted: May 30, 2008
• Study Start: September 1, 2007
• Primary Completion: June 1, 2010
• Study Completion: September 1, 2010
• Last Updated: June 17, 2008

Record last verified: 2008-05

Locations

CN (1)