NCT00681902

Brief Summary

The purpose of this study is to explore to what degree, if any, Jet lidocaine will reduce or alleviate pain, as compared to Jet normal saline, in children undergoing needle insertion in the Pediatric Emergency Department (PED). If effective, Jet lidocaine would afford a novel rapidly acting local anesthesic for children in the PED.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
150

participants targeted

Target at P75+ for not_applicable pain

Timeline
Completed

Started Mar 2007

Typical duration for not_applicable pain

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2007

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2007

Completed
7 months until next milestone

First Submitted

Initial submission to the registry

May 19, 2008

Completed
2 days until next milestone

First Posted

Study publicly available on registry

May 21, 2008

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2008

Completed
Last Updated

February 6, 2009

Status Verified

February 1, 2009

Enrollment Period

8 months

First QC Date

May 19, 2008

Last Update Submit

February 4, 2009

Conditions

Keywords

PediatricPainNeedleEmergencyPhlebotomyIntravenousLidocaineLocalAnesthesia

Outcome Measures

Primary Outcomes (1)

  • Pain, the primary outcome, will be assessed using the Color Analogue pain Scale before and after needle insertion in each group and compared for a clinically significant difference.

    Primary outcome was measured at time of initial needlestick in ED

Secondary Outcomes (1)

  • Provider and patient satisfaction.

    Secondary outcome was measured at time of initial needlestick in ED.

Study Arms (2)

1

EXPERIMENTAL

Jet lidocaine

Drug: Lidocaine

2

PLACEBO COMPARATOR

Jet saline

Drug: Placebo

Interventions

Jet lidocaine compared to jet placebo before needle insertion

Also known as: National medical jet injector system
1

Jet saline

2

Eligibility Criteria

Age5 Years - 19 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • Age 5 - 18 years
  • Evaluation and treatment requiring needle insertion in \<60 minutes (Patient is not a candidate for EMLA cream)
  • Parent or patient consent, and child assent

You may not qualify if:

  • Age \<5 years or \>18 years
  • Children eligible for or receiving EMLA cream
  • Significant blunt or penetrating trauma requiring rapid evaluation/resuscitation (GCS\<15)
  • Unstable shock
  • Altered sensorium or intoxication
  • History of allergy to Lidocaine
  • Neurologic deficit involving a lack of sensation in area of insertion
  • Developmental delay so as not to understand pain scale

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Bellevue Hospital

New York, New York, 10016, United States

Location

MeSH Terms

Conditions

PainEmergencies

Interventions

Lidocaine

Condition Hierarchy (Ancestors)

Neurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and SymptomsDisease AttributesPathologic Processes

Intervention Hierarchy (Ancestors)

AcetanilidesAnilidesAmidesOrganic ChemicalsAniline CompoundsAmines

Study Officials

  • Michael Mojica

    NYU/Bellevue

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
QUADRUPLE
Who Masked
PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER

Study Record Dates

First Submitted

May 19, 2008

First Posted

May 21, 2008

Study Start

March 1, 2007

Primary Completion

November 1, 2007

Study Completion

July 1, 2008

Last Updated

February 6, 2009

Record last verified: 2009-02

Locations