Preventing HIV/Aids in Drug Abusing Youth

NCT00680719 | Completed Phase 1

• 1 other identifier: DA17023
• Study Type: interventional
• Target: 111
• Locations: 1 country
• Sites: 1

Brief Summary

This project involves two studies focusing on the engagement and treatment of adolescents diagnosed with substance use disorders. Study 1 will evaluate a promising parent-based engagement intervention, Community Reinforcement Training, designed to facilitate the entry of resistant drug-abusing adolescents in treatment. The approach will be compared with an Engagement As Usual intervention condition. Study 2 involves a controlled clinical trial evaluating the efficacy of an HIV/AIDS prevention intervention embedded in family-based drug abuse treatment for reducing HIV/AIDS risk behaviors and substance use. Adolescents who are successfully engaged in treatment through Study 1 will be randomly assigned to receive either family therapy alone or family therapy with the integrated HIV/AIDS prevention intervention. Both studies are being conducted in Portland, Oregon.

Conditions

HIV Infections

Keywords

substance abuse; HIV risk; Behavior and Mental Disorders; HIV Seronegativity

Outcome Measures

Primary Outcomes (1)

• Changes in adolescent's substance use.

  12 months

Secondary Outcomes (1)

• Changes in HIV risk behaviors.

  12 months

Study Arms (2)

1

ACTIVE COMPARATOR

Family Therapy plus HIV prevention

Behavioral: IBFT /HIV prevention

2

ACTIVE COMPARATOR

Family Therapy only.

Behavioral: IBFT

Interventions

IBFT /HIV prevention BEHAVIORAL

Integrated Behavioral and Family Therapy (IBGT) with HIV prevention.

1

IBFT BEHAVIORAL

Integrated Behavioral and Family Therapy (IBFT).

2

Eligibility Criteria

• Age: 15 Years - 20 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64)

You may qualify if:

• Parents have an adolescent in the ages of 15-20 years.
• Have had contact with the adolescent on at least 40% of the past 90 days.
• Have some knowledge or evidence that the adolescent would meet DSM-IV diagnostic criteria for a substance abuse disorder.
• Adolescent has explicitly refused to attend any intake or therapy sessions.
• All parents' efforts to enter adolescent into treatment have failed, despite therapist's assistance.
• Residence in Portland vicinity.
• Sufficient residential stability to permit probable contact at follow-up. (e.g. not homeless at time of intake)

You may not qualify if:

• Evidence of psychotic or organic state of sufficient severity to interfere with understanding of study instruments and procedures.
• Adolescent has received residential drug treatment longer than a 2-week period in the past 90 days.

Sponsors & Collaborators

• Oregon Research Institute: lead
• National Institute on Drug Abuse (NIDA): collaborator

Study Sites (1)

Oregon Research Institute Center for Family and Adolescent Research

Portland, Oregon, 97205, United States

Location

MeSH Terms

Conditions

HIV Infections; Substance-Related Disorders; Behavior; Mental Disorders

Condition Hierarchy (Ancestors)

Blood-Borne Infections; Communicable Diseases; Infections; Sexually Transmitted Diseases, Viral; Sexually Transmitted Diseases; Lentivirus Infections; Retroviridae Infections; RNA Virus Infections; Virus Diseases; Genital Diseases; Urogenital Diseases; Immunologic Deficiency Syndromes; Immune System Diseases; Chemically-Induced Disorders

Study Officials

• Holly B Waldron, Ph.D.

  Oregon Research Institute

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: phase 1
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 16, 2008
• First Posted: May 20, 2008
• Study Start: June 1, 2004
• Primary Completion: June 1, 2013
• Study Completion: June 1, 2013
• Last Updated: August 5, 2014

Record last verified: 2014-08

Locations

US (1)