NCT00675493

Brief Summary

This trial is conducted in Europe. The aim of this observational study is to evaluate the blood glucose control (HbA1c) using NovoMix® 30 for treatment of type 1 and type 2 diabetes under normal clinical practice conditions in Romania.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
942

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started May 2008

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 2008

Completed
6 days until next milestone

First Submitted

Initial submission to the registry

May 7, 2008

Completed
2 days until next milestone

First Posted

Study publicly available on registry

May 9, 2008

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2009

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2009

Completed
Last Updated

February 19, 2016

Status Verified

February 1, 2016

Enrollment Period

8 months

First QC Date

May 7, 2008

Last Update Submit

February 18, 2016

Conditions

Outcome Measures

Primary Outcomes (1)

  • Change in HbA1c from baseline

    For the duration of the study

Secondary Outcomes (8)

  • Percentage of subjects achieving HbA1c below 7.0% and below or equal to 6.5%

    after 12 weeks and 24 weeks of treatment

  • Change in FPG (glucose variability)

    after 12 weeks and 24 weeks of treatment

  • Change in PPG (postprandial control)

    after 12 weeks and 24 weeks of treatment

  • Change in insulin dose and number of injections

    at 12 weeks and 24 weeks of treatment

  • Change in oral antidiabetic drug therapy

    after 12 weeks and 24 weeks of treatment

  • +3 more secondary outcomes

Study Arms (1)

A

Drug: biphasic insulin aspart 30

Interventions

Start dose and frequency prescribed by the physician as a result of a normal clinical evaluation

Also known as: NovoMix® 30
A

Eligibility Criteria

Age10 Years - 75 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Type 1 and type 2 diabetes patients inadequately controlled on human premixes

You may qualify if:

  • Type 1 and type 2 diabetics who are treated with human premix insulin (the selection of the subjects will be at the discretion of the individual physician).

You may not qualify if:

  • Subjects currently being treated with biphasic insulin aspart 30
  • Subjects who were previously enrolled in this study
  • Subjects with a hypersensitivity to biphasic insulin aspart 30 or to any of the excipients
  • Women who are pregnant or have the intention of becoming pregnant within next 6 months
  • Children below 10 years of age

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Unknown Facility

Bucharest, 010031, Romania

Location

Related Links

MeSH Terms

Conditions

Diabetes MellitusDiabetes Mellitus, Type 1Diabetes Mellitus, Type 2

Interventions

insulin aspart, insulin aspart protamine drug combination 30:70

Condition Hierarchy (Ancestors)

Glucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System DiseasesAutoimmune DiseasesImmune System Diseases

Study Officials

  • Global Clinical Registry (GCR, 1452)

    Novo Nordisk A/S

    STUDY DIRECTOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 7, 2008

First Posted

May 9, 2008

Study Start

May 1, 2008

Primary Completion

January 1, 2009

Study Completion

January 1, 2009

Last Updated

February 19, 2016

Record last verified: 2016-02

Locations