Clinical and Cost Effectiveness of Brief Cognitive-Behavioral Therapy (CBT) for Pediatric Internalizing Disorders

NCT00669526 | Completed Phase 2

• 1 other identifier: 051653
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

This project assesses the clinical and cost effectiveness of brief cognitive-behavioral therapy (CBT) for depressed (ages 11-17) and anxious (ages 8-17) youths seen for services in pediatric primary care. This study is designed to compare the impact of brief CBT delivered on-site in pediatric primary care to referral to specialty mental health care (SMHC), as well as obtain an estimate of the total costs of the CBT protocols for depression and anxiety and the cost-effectiveness of the protocols compared to referral to and utilization of SMHC services.

Conditions

Depression; Anxiety

Keywords

anxiety; depression; Major Depressive Disorder; child; adolescent; CBT; Cognitive-Behavioral Therapy; primary care

Outcome Measures

Primary Outcomes (1)

• Clinician Global Impressions - Improvement (CGI-I)

  weeks 12 and 24

Study Arms (2)

SMHC referral

ACTIVE COMPARATOR

Referral to local Specialty Mental Health Care Services

Behavioral: SMHC referral

BCBT

EXPERIMENTAL

Brief Cognitive Behavioral Therapy

Behavioral: BCBT

Interventions

BCBT BEHAVIORAL

Brief Cognitive Behavioral Therapy. This BCBT protocol consists of up to 8 CBT sessions to be conducted over a maximum of 12 weeks.

Also known as: CBT, Cognitive-Behavioral Therapy

BCBT

SMHC referral BEHAVIORAL

Referral to local Speciality Mental Health Care. Families were referred to local mental health care providers, and could freely choose any treatment or combination of treatments offered (e.g., anti-depressant medication, individual psychotherapy, family psychotherapy, etc.).

SMHC referral

Eligibility Criteria

• Age: 7 Years - 17 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)

You may qualify if:

• Ages 11 to 17 years
• Meet diagnostic criteria for Major Depression, Dysthymia, or Minor Depression
• Live with a legal guardian
• Ages 7 to 17 years
• Meet full or probable (missing one, non-core symptom) diagnostic criteria for Separation Anxiety Disorder, Generalized Anxiety Disorder, Social Phobia, or Specific Phobia
• Live with a legal guardian

You may not qualify if:

• Require treatment other than brief CBT (namely, youths with bipolar disorder, psychosis, active suicidal ideation with plan, post-traumatic stress disorder, substance dependence, or mental retardation
• Experience of recent physical or sexual maltreatment
• Serious or unstable physical illness
• Current participation in an alternate, active intervention for the target condition of interest

Sponsors & Collaborators

• Robert Wood Johnson Foundation: lead
• National Institute of Mental Health (NIMH): collaborator
• William T. Grant Foundation: collaborator

Study Sites (1)

University of Pittsburgh Medical Center

Pittsburgh, Pennsylvania, 15213, United States

Location

Related Publications (1)

• Weersing, V. R., Gonzalez, A., Campo, J. V., & Lucas, A. N. Brief Behavioral Therapy for Pediatric Anxiety and Depression: Piloting an Integrated Treatment Approach. Cognitive and Behavioral Practice (in press), 2008.

  BACKGROUND

Related Links

• The National Institute of Mental Health (NIMH) is the largest scientific organization in the world dedicated to research focused on the understanding, treatment, and prevention of mental disorders and the promotion of mental health.
• The Robert Wood Johnson Foundation (RWJF) focuses on the pressing health and health care issues facing our country.
• William T. Grant Foundation's mission focuses on improving the lives of youth ages 8 to 25 in the United States. We accomplish this by providing grants primarily for high-quality empirical studies.

MeSH Terms

Conditions

Depression; Anxiety Disorders; Depressive Disorder, Major

Interventions

Cognitive Behavioral Therapy

Condition Hierarchy (Ancestors)

Behavioral Symptoms; Behavior; Mental Disorders; Depressive Disorder; Mood Disorders

Intervention Hierarchy (Ancestors)

Behavior Therapy; Psychotherapy; Behavioral Disciplines and Activities

Study Officials

• V. Robin Weersing, Ph.D.

  SDSU/UCSD Joint Doctoral Program in Clinical Psychology

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: phase 2
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: April 28, 2008
• First Posted: April 30, 2008
• Study Start: October 1, 2004
• Primary Completion: March 1, 2007
• Study Completion: April 1, 2007
• Last Updated: April 30, 2008

Record last verified: 2008-04

Locations

US (1)