NCT00642785

Brief Summary

The research question to be addressed is whether indirect phototherapy based activation of the body's alternative cellular energy (ACE) pathway will lead to expedited healing of active herpes simplex virus (HSV) and herpes zoster virus (HZV)skin lesions, and also possibly inhibit both latent HSV infections and residual HZV infections.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
500

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 2008

Shorter than P25 for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2008

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

March 19, 2008

Completed
6 days until next milestone

First Posted

Study publicly available on registry

March 25, 2008

Completed
7 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2008

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2008

Completed
Last Updated

June 3, 2008

Status Verified

May 1, 2008

Enrollment Period

3 months

First QC Date

March 19, 2008

Last Update Submit

May 30, 2008

Conditions

Keywords

herpesHSVzosterHZVshingles

Outcome Measures

Primary Outcomes (1)

  • Expedited healing of active lesions

    Within 1 day following therapy

Secondary Outcomes (1)

  • Recurrence of lesions and/or symptoms

    3 months

Study Arms (4)

1

Patients with active oral or genital HSV skin lesions

2

Patients with a history of recurrent oral or genital HSV but without an active lesion at the time of treatment

3

Patients with active shingles/zoster

4

Patients with post herpetic neuralgia

Eligibility Criteria

Age18 Years - 70 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

HSV and HZV infected patients

You may qualify if:

  • Clinical diagnosis of active, latent or residual HSV or HZV infection

You may not qualify if:

  • Unwilling or unable to provide Informed Consent

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (1)

  • Martin WJ, Stoneburner J. Symptomatic relief of herpetic skin lesions utilizing an energy-based approach to healing. Exp Mol Pathol. 2005 Apr;78(2):131-4. doi: 10.1016/j.yexmp.2004.10.007. Epub 2005 Jan 5.

    PMID: 15713438BACKGROUND

MeSH Terms

Conditions

Herpes SimplexHerpes Zoster

Condition Hierarchy (Ancestors)

Herpesviridae InfectionsDNA Virus InfectionsVirus DiseasesInfectionsSkin Diseases, ViralSkin Diseases, InfectiousSkin DiseasesSkin and Connective Tissue DiseasesVaricella Zoster Virus Infection

Study Officials

  • W John Martin, MD, PhD

    Institute of Progressive Medicine

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER

Study Record Dates

First Submitted

March 19, 2008

First Posted

March 25, 2008

Study Start

January 1, 2008

Primary Completion

April 1, 2008

Study Completion

April 1, 2008

Last Updated

June 3, 2008

Record last verified: 2008-05