NCT00631956

Brief Summary

The purpose of this study is to determine the progression evaluation, cardiovascular outcomes, and genetic determinations of hypertension in Chinese

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
1,038

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Oct 2006

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2006

Completed
1.4 years until next milestone

First Submitted

Initial submission to the registry

March 3, 2008

Completed
7 days until next milestone

First Posted

Study publicly available on registry

March 10, 2008

Completed
8.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2016

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2016

Completed
Last Updated

April 7, 2016

Status Verified

March 1, 2016

Enrollment Period

10.2 years

First QC Date

March 3, 2008

Last Update Submit

April 5, 2016

Conditions

Hypertension

Eligibility Criteria

Age40 Years - 70 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

A follow-up genetic study of Taiwan SAPPHIRe Cohort

You may qualify if:

  • Age of subjects when recruited must be between 35 and 60 years. Subjects over age 60 may also be eligible provided that documentation of their hypertension status prior to age 60 is available.
  • Chinese ancestry, i.e. all four grandparents Chinese. Hypertension is defined as follows: systolic BP (SBP) greater than or equal to (\>=) 160 mm Hg or diastolic BP (DBP) \>= 95 mm Hg or taking 2 medications for high blood pressure (Stage II hypertension). Alternatively the subject could have uncontrolled hypertension, i.e. taking 1 medication for high blood pressure and has either systolic BP \>= 140 or diastolic \>= 90 mm Hg.

You may not qualify if:

  • One of the affected sibs is adopted (i.e. no parent in common) or if the sibs have only one parent in common.
  • A body-mass index greater than 35.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Division of Biostatistics and Bioinformatics, NHRI

Miaoli County, 350, Taiwan

Location

Biospecimen

Retention: SAMPLES WITH DNA

Plasma, serum, urine, and buffy coat

MeSH Terms

Conditions

Hypertension

Condition Hierarchy (Ancestors)

Vascular DiseasesCardiovascular Diseases

Study Officials

  • Chao Hsiung, PhD

    Division of Biostatistics and Bioinformatics, National Health Research Institutes

    STUDY DIRECTOR

Study Design

Study Type
observational
Observational Model
FAMILY BASED
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 3, 2008

First Posted

March 10, 2008

Study Start

October 1, 2006

Primary Completion

December 1, 2016

Study Completion

December 1, 2016

Last Updated

April 7, 2016

Record last verified: 2016-03

Locations

TW(1)