Examining How Heart Disease Risk Factors Affect Healthy Aging (The Chicago Healthy Aging Study [CHAS])

NCT00626379 | Completed

• 2 other identifiers: 1379R01HL081141-04
• Study Type: observational
• Target: 1,395
• Locations: 1 country
• Sites: 1

Brief Summary

Heart disease is the leading cause of death in the United States and is responsible for 30% of all deaths in the United States. This study will examine how risk factors for heart disease in young and middle aged people affect people's health as they grow older.

Conditions

Coronary Disease; Cardiovascular Diseases

Keywords

Coronary Heart Disease; Subclinical Atherosclerosis; CVD-Related Markers of Inflammation; Mortality

Outcome Measures

Primary Outcomes (1)

• Subclinical atherosclerosis, CVD-related markers of inflammation, and levels of physical performance

  Measured during participant's one (baseline) study visit

Eligibility Criteria

• Age: 65 Years - 84 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Original participants in the Chicago Heart Association (CHA) Detection in Industry study (1967 to 1973) who still reside in the Greater Chicagoland area.

You may qualify if:

• Participated in the CHA study
• Lives in the Greater Chicagoland area

You may not qualify if:

• Severely ill, disabled, or cognitively impaired

Sponsors & Collaborators

• Northwestern University: lead
• National Heart, Lung, and Blood Institute (NHLBI): collaborator

Study Sites (1)

Preventive Medicine Research Clinic

Chicago, Illinois, 60611, United States

Location

Biospecimen

Retention: SAMPLES WITH DNA

Whole blood, serum, white cells, and urine

MeSH Terms

Conditions

Coronary Disease; Cardiovascular Diseases

Condition Hierarchy (Ancestors)

Myocardial Ischemia; Heart Diseases; Vascular Diseases

Study Officials

• Martha L. Daviglus, MD, PhD

  Northwestern University Feinberg School of Medicine

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: February 27, 2008
• First Posted: February 29, 2008
• Study Start: November 1, 2007
• Primary Completion: August 1, 2010
• Study Completion: December 1, 2010
• Last Updated: May 3, 2023

Record last verified: 2023-05

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)