NCT00623090

Brief Summary

Prostate cancer (PCa) is the leading cancer diagnosis among men and the second leading cause of male cancer death. However, screening asymptomatic men remains controversial, as early diagnosis and treatment of PCa has not yet demonstrated reduced disease-related mortality in a randomized trial. The goal of the current study is to develop and assess widely accessible methods to assist men in making informed decisions about PCa screening. We will compare the efficacy of a new web-based, interactive decision support approach to our existing print-based PCa screening decision tool, among a diverse sample of male primary care patients. Abundant evidence documents the expanding role of the Internet in increasing access to and understanding of health information and the need for systematic evaluations of Internet-based interventions. A novel aspect of the proposed trial will be our focus on cognitive biases as a factor that has limited the success of previous information-based interventions. Specifically, we will evaluate: 1) confirmation bias and 2) short-term consequences bias.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,893

participants targeted

Target at P75+ for phase_3 prostate-cancer

Timeline
Completed

Started Oct 2007

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2007

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

February 14, 2008

Completed
11 days until next milestone

First Posted

Study publicly available on registry

February 25, 2008

Completed
3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2011

Completed
5 months until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2011

Completed
Last Updated

December 13, 2012

Status Verified

December 1, 2012

Enrollment Period

3.4 years

First QC Date

February 14, 2008

Last Update Submit

December 11, 2012

Conditions

Keywords

prostate cancer screening educationbehavioral oncologyrandomized trial

Outcome Measures

Primary Outcomes (3)

  • screening decision

    one-year follow up

  • knowledge about prostate cancer screening

    one-month and one-year post-intervention

  • decisional satisfaction

    one-month and one-year post intervention

Study Arms (3)

1 Website

EXPERIMENTAL

Participants receive the Login information for the Internet we developed on prostate cancer screening.

Behavioral: educational internet site on prostate cancer screening

2 Booklet

ACTIVE COMPARATOR

Participants receive the education booklet we developed on prostate cancer screening.

Behavioral: Educational print booklet

3 Usual Care

PLACEBO COMPARATOR

Usual care: participants receive no intervention.

Behavioral: Usual care

Interventions

Healthy men between 45-70 receive the login information to access our educational internet site on prostate cancer screening.

1 Website

Healthy men between 45-70 receive a copy of our educational print booklet in the mail.

2 Booklet
Usual careBEHAVIORAL

Healthy men aged 45-70 receive no intervention and are followed for one year, along with the men in the two intervention arms.

3 Usual Care

Eligibility Criteria

Age45 Years - 70 Years
Sexmale
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Active primary care patients at Georgetown University Medical Center, Washington Hospital Center, or Medstar Physician Partners (I,e, seen during the past two years)
  • English-speaking
  • years of age; AND
  • Ability to provide meaningful consent.

You may not qualify if:

  • History of prostate cancer.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Georgetown University Medical Center

Washington D.C., District of Columbia, 20007, United States

Location

Washington Hospital Center

Washington D.C., District of Columbia, 20010, United States

Location

Related Publications (1)

  • Dorfman CS, Williams RM, Kassan EC, Red SN, Dawson DL, Tuong W, Parker ER, Ohene-Frempong J, Davis KM, Krist AH, Woolf SH, Schwartz MD, Fishman MB, Cole C, Taylor KL. The development of a web- and a print-based decision aid for prostate cancer screening. BMC Med Inform Decis Mak. 2010 Mar 3;10:12. doi: 10.1186/1472-6947-10-12.

MeSH Terms

Conditions

Prostatic Neoplasms

Condition Hierarchy (Ancestors)

Genital Neoplasms, MaleUrogenital NeoplasmsNeoplasms by SiteNeoplasmsGenital Diseases, MaleGenital DiseasesUrogenital DiseasesProstatic DiseasesMale Urogenital Diseases

Study Officials

  • Kathryn L. Taylor, PhD

    Georgetown University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 3
Allocation
RANDOMIZED
Masking
NONE
Purpose
SCREENING
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor

Study Record Dates

First Submitted

February 14, 2008

First Posted

February 25, 2008

Study Start

October 1, 2007

Primary Completion

March 1, 2011

Study Completion

August 1, 2011

Last Updated

December 13, 2012

Record last verified: 2012-12

Locations