NCT00622882

Brief Summary

The primary objective is to determine if early infectious disease (ID) consultation (defined as within 48 hours of a positive blood culture) will reduce mortality rates from Staphylococcus aureus bacteremia (SAB). This study will also determine if such consultations could reduce the duration of hospitalisation, recurrence and financial costs in patients with this infection.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
200

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Oct 2007

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2007

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

February 13, 2008

Completed
12 days until next milestone

First Posted

Study publicly available on registry

February 25, 2008

Completed
7.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2015

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2015

Completed
Last Updated

January 7, 2014

Status Verified

January 1, 2014

Enrollment Period

8.2 years

First QC Date

February 13, 2008

Last Update Submit

January 6, 2014

Conditions

Staphylococcus Aureus Bacteremia

Keywords

Staphylococcus aureusBacteremiaOutcomeMortalityRecurrenceInfectious Diseases specialists

Outcome Measures

Primary Outcomes (1)

  • mortality

    1 year

Secondary Outcomes (3)

  • recurrence

    2 year

  • duration of hospitalisation

    1 year

  • financial costs of hospitalisation

    1 year

Study Arms (2)

ID

ACTIVE COMPARATOR

Patients receiving an early Infectious disease consultation ( within first 48 hours of a positive blood culture)

Other: infectious disease specialist consultation

NO ID

NO INTERVENTION

Includes those patients who do not receive an Infectious disease consultation in the first 48 hours

Interventions

infectious disease specialist consultationOTHER

Randomised trial to determine the utility of an early Infectious disease Consultation in Staphylococcus aureus bacteremic patients ( in the first 48 hours of a positive blood culture)

Also known as: Health Services
ID

Eligibility Criteria

Age1 Month+
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • All inpatients at the National University Hospital with Staphylococcus aureus (both methicillin sensitive and methicillin resistant) bacteremia isolated within the defined time period

You may not qualify if:

  • Patients who died or were discharged before the notification from the laboratory
  • Neonates
  • Polymicrobial bacteremia

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

National University Hospital

Singapore, 11974, Singapore

RECRUITING

MeSH Terms

Conditions

Staphylococcal InfectionsBacteremiaRecurrence

Interventions

Health Services

Condition Hierarchy (Ancestors)

Gram-Positive Bacterial InfectionsBacterial InfectionsBacterial Infections and MycosesInfectionsSepsisSystemic Inflammatory Response SyndromeInflammationPathologic ProcessesPathological Conditions, Signs and SymptomsDisease Attributes

Intervention Hierarchy (Ancestors)

Health Care Facilities Workforce and Services

Study Officials

  • Paul A Tambyah, MD

    National University of Singapore

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Paul A Tambyah, MD

CONTACT

(65)67724375mdcpat@nus.edu.sg

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor Paul Ananth Tambyah

Study Record Dates

First Submitted

February 13, 2008

First Posted

February 25, 2008

Study Start

October 1, 2007

Primary Completion

December 1, 2015

Study Completion

December 1, 2015

Last Updated

January 7, 2014

Record last verified: 2014-01

Locations

SG(1)