NCT00619632

Brief Summary

This is a randomized, controlled, single-center, single-blind, 2x2 factorial design trial of routine provider, primary care-based interventions to increase breastfeeding intensity up to 6 months in low-income multiethnic women, with stratification for maternal country of birth. The Best Infant Nutrition for Good Outcomes (BINGO) trial will randomize women into one of four treatment groups: (a) Prenatal Care Provider (PNC); (b) Lactation Consultant (LC); (c) PNC + LC, or; (d) Control. Thus, the separate and synergistic effects of the interventions will be tested, compared to a Control standard of care. The intervention and design build upon our prior trial of an LC intervention alone. PNCs- certified nurse midwives and ob/gyns-- will use a brief, electronically prompted protocol with women in the PNC, and PNC + LC groups throughout pregnancy. An LC will arrange pre-natal one-on-one meetings, daily hospital, and home visits with women in the LC and PNC+LC groups. Descriptive data on infant health visits, and participant/provider experiences will be collected as secondary outcomes. Interviews at 1,3 and 6 months post-partum will collect infant feeding, and health visit data outside the medical center. Medical center visit data will be obtained from MIS data. Primary Outcomes (Hypotheses): Breastfeeding

  1. 1.Breastfeeding Intensity at 1,3, and 6 Months
  2. 2.Exclusive Breastfeeding at 1,3, and 6 Months
  3. 3.To describe the frequency and timing of infant health visits for "breast-feeding sensitive" illnesses
  4. 4.To describe participant and provider (LC and PNC) experience of the interventions.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
666

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Feb 2008

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2008

Completed
3 days until next milestone

First Submitted

Initial submission to the registry

February 4, 2008

Completed
17 days until next milestone

First Posted

Study publicly available on registry

February 21, 2008

Completed
5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2013

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2013

Completed
Last Updated

January 14, 2015

Status Verified

January 1, 2015

Enrollment Period

5 years

First QC Date

February 4, 2008

Last Update Submit

January 13, 2015

Conditions

Outcome Measures

Primary Outcomes (1)

  • Breastfeeding duration and intensity

    Assessed at 1,3, and 6 months

Secondary Outcomes (2)

  • Infant health visits

    12 months

  • Patient and provider experiences of the interventions

    6 months

Study Arms (4)

1

EXPERIMENTAL

LC- Primary-care based lactation consultant meeting women pre- and post-natally.

Behavioral: Lactation Consultant

2

EXPERIMENTAL

Provider Prompt

Behavioral: Provider Prompt

3

EXPERIMENTAL

LC+Provider Prompt

Behavioral: LC+ Provider Prompt

Control

NO INTERVENTION

Interventions

Lactation consultant- primary care based, meets with women pre-natally, in the hospital, and at home up to 6 months post-partum.

1
Provider PromptBEHAVIORAL

Prompt in electronic prenatal record will appear 5 times throughout pregnancy re: up to 10 open-ended discussion points for provider to raise

2

Participants in this group receive both the LC and Provider Prompt interventions.

3

Eligibility Criteria

Age18 Years+
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Enrolled/plan to remain in care at the site throughout their pregnancy
  • st or 2nd trimester (randomization will include trimester as a blocking factor)
  • Aged 18 or older
  • Can provide a reliable phone number and at least 2 alternative contacts
  • Are carrying a singleton pregnancy
  • Can communicate in English or Spanish

You may not qualify if:

  • High risk of prematurity/NICU (e.g., ESRD, multiple prior preterms, congenital anomalies)
  • Medical/obstetrical complications for which BF is or may be perceived to be contra-indicated (e.g., HIV+, HTLV-1, breast reduction surgery, Hepatitis B and C, pre-gestational diabetes )
  • On chronic medications incompatible with BF (e.g., hypoglycemics, lithium, ciprofloxacin)
  • Enrolled in site's Group Pre-natal Care (app. 60 women/year)
  • Previously enrolled in MILK study
  • Reported use of street drugs (responds to reviewer comment of how to control for this)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Comprehensive Family Care Center

The Bronx, New York, 10461, United States

Location

Related Publications (2)

  • Bonuck K, Stuebe A, Barnett J, Labbok MH, Fletcher J, Bernstein PS. Effect of primary care intervention on breastfeeding duration and intensity. Am J Public Health. 2014 Feb;104 Suppl 1(Suppl 1):S119-27. doi: 10.2105/AJPH.2013.301360. Epub 2013 Dec 19.

  • Andaya E, Bonuck K, Barnett J, Lischewski-Goel J. Perceptions of primary care-based breastfeeding promotion interventions: qualitative analysis of randomized controlled trial participant interviews. Breastfeed Med. 2012 Dec;7(6):417-22. doi: 10.1089/bfm.2011.0151. Epub 2012 May 23.

MeSH Terms

Conditions

Breast Feeding

Condition Hierarchy (Ancestors)

Feeding BehaviorBehavior

Study Officials

  • Karen A. Bonuck, PhD

    Albert Einstein College of Medicine

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
FACTORIAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
PI

Study Record Dates

First Submitted

February 4, 2008

First Posted

February 21, 2008

Study Start

February 1, 2008

Primary Completion

February 1, 2013

Study Completion

February 1, 2013

Last Updated

January 14, 2015

Record last verified: 2015-01

Locations