The Role of Impact Activity in Peripubertal Bone Accrual

NCT00619047 | Completed

• 1 other identifier: Bone Density Study
• Study Type: observational
• Target: 131
• Locations: 1 country
• Sites: 1

Brief Summary

Osteoporosis has been established as a major public health problem, primarily effecting women. The attainment of maximal peak bone mass is crucial in the prevention of osteoporosis, yet little is known about the specifics of bone accrual. Physical activity has been identified as an important modifiable factor controlling bone accrual. It is has been shown that increased activity during peri-pubertal years increase bone mineral content during adulthood. Thus, strategies designed to increase peak bone mass should target the peri-pubertal years of critical bone acquisition. Hypothesis 1a: The amount of bone mineral accrued during the peri-pubertal years is greater in girls who engage in impact activity than in those who do not. Hypothesis 1b: The positive effects of impact activity on bone accrual are maintained after cessation of the activity, resulting in greater bone mineral density in girls who participate in impact activity during a portion of the peri-pubertal years than in those who never participated in impact activity.

Conditions

Bone Mineral Density

Study Arms (1)

Observation

Eligibility Criteria

• Age: 10 Years - 12 Years
• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Child (0-17)
• Sampling Method: Probability Sample

Study Population

Subjects were recruited into the following three groups based on their exposure to gymnastic activity. A) control, no gymnastic activity. B)retired gymnasts, who participated at study onset, but stopped gymnastics activity during the course of the study. C) active gymnast, who continues participation in gymnastics throughout the duration of the study.

You may qualify if:

• Subjects between the ages of 10-12 will be asked to participate

Sponsors & Collaborators

• State University of New York - Upstate Medical University: lead

Study Sites (1)

Institute for Human Performance

Syracuse, New York, 13210, United States

Location

Study Officials

• Tamara A Scerpella, MD

  State University of New York - Upstate Medical University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: February 6, 2008
• First Posted: February 20, 2008
• Study Start: January 1, 2002
• Primary Completion: August 1, 2008
• Study Completion: August 1, 2008
• Last Updated: November 20, 2009

Record last verified: 2009-11

Locations

US (1)