NCT00615082

Brief Summary

The primary goals of this exploratory/developmental (R21) study are to evaluate the feasibility and acceptability of a MBSR intervention for caregivers of patients with dementia, and to estimate the effectiveness of program outcomes on standardized measures of perceived stress, psychological distress and caregiver burden. We will randomize 60 caregivers 1:1 to participate in: 1.) an intervention arm consisting of a MBSR program that includes 8 weeks of group instruction in mindfulness meditation techniques followed by home practice, or 2.) an active control arm consisting of a standard 8 week Community Caregiver Education and Support (CESS) program.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
78

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Feb 2007

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2007

Completed
1 year until next milestone

First Submitted

Initial submission to the registry

February 1, 2008

Completed
13 days until next milestone

First Posted

Study publicly available on registry

February 14, 2008

Completed
1.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2009

Completed
1.8 years until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2011

Completed
Last Updated

September 7, 2023

Status Verified

September 1, 2011

Enrollment Period

2.2 years

First QC Date

February 1, 2008

Last Update Submit

September 1, 2023

Conditions

Outcome Measures

Primary Outcomes (1)

  • Evaluate the feasibility of conducting a trial comparing mindfulness-based stress reduction (MBSR) and community caregiver education and support (CESS) programs on stress reduction for caregivers of patients with dementia.

    participants will complete surveys and consent to a blood draw at baseline, post intervention, and 6 months. They will complete a daily health behaviors calendar, and a subset will track their daily blood pressure.

    through study completion, an average of 1 year

Secondary Outcomes (1)

  • Estimate the effectiveness of a MBSR program compared to a standard CESS program for caregivers of persons with dementia.

    through study completion, an average of 1 year

Study Arms (2)

Mindfulness-Based Stress Reduction

EXPERIMENTAL

Behavioral: Mindfulness-Based Stress Reduction Other Names: MBSR An 8-week course led by an experienced instructor in a group format of up to 15 people. Participants in the MBSR course learn mindfulness meditation techniques and simple yoga exercises such as stretching.

Behavioral: Mindfulness-Based Stress Reduction

Caregiver Education & Social Support

ACTIVE COMPARATOR

Behavioral: Caregiver Education \& Social Support Other Names: CESS An 8-week course led by experienced instructors in a group format of up to 15 people. Participants in the CESS course learn about a variety of important issues related to elder care and receive social and emotional support in a group discussion format.

Behavioral: Caregiver Education & Social Support

Interventions

An 8-week course led by an experienced instructor in a group format of up to 15 people. Participants in the MBSR course learn mindfulness meditation techniques and simple yoga exercises such as stretching.

Also known as: MBSR
Mindfulness-Based Stress Reduction

An 8-week course led by experienced instructors in a group format of up to 15 people. Participants in the CESS course learn about a variety of important issues related to elder care and receive social and emotional support in a group discussion format.

Also known as: CESS
Caregiver Education & Social Support

Eligibility Criteria

Age21 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • adult, 21 or older
  • caregiver for a community dwelling patient with dementia
  • English speaking
  • literate - able to read course materials
  • mentally intact with no history of mental illness
  • reachable by phone
  • able to attend weekly classes in the Bloomington area
  • interested in either type of program (psycho-educational/mind-body intervention)
  • willing to complete an informed consent process
  • willing to be randomized and participate in one of two interventions
  • experiencing significant stress (scale of 1-10 score of 5 or higher)

You may not qualify if:

  • have previously participated in a community caregiver education and support group
  • have previously completed formal training in other mind body practices such as meditation, yoga, or tai chi, or who are currently practicing
  • are regularly practicing mindfulness meditation
  • express uncertainty that they can attend the intervention on a regular basis
  • not experiencing significant stress

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

HealthPartners Research Foundation

Bloomington, Minnesota, 55425, United States

Location

MeSH Terms

Conditions

Dementia

Interventions

Mindfulness-Based Stress Reduction

Condition Hierarchy (Ancestors)

Brain DiseasesCentral Nervous System DiseasesNervous System DiseasesNeurocognitive DisordersMental Disorders

Intervention Hierarchy (Ancestors)

MindfulnessCognitive Behavioral TherapyBehavior TherapyPsychotherapyBehavioral Disciplines and Activities

Study Officials

  • Robin Whitebird, PhD

    HealthPartners Institute

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 1, 2008

First Posted

February 14, 2008

Study Start

February 1, 2007

Primary Completion

May 1, 2009

Study Completion

March 1, 2011

Last Updated

September 7, 2023

Record last verified: 2011-09

Locations