NCT00614796

Brief Summary

Chronic Obstructive Pulmonary Disease (COPD) is increasing in the Netherlands. COPD is characterized by a deterioration of lung function, a lowering physical activity level and a low state of quality of life. The aim of this randomized controlled study is to investigate the effects of a structured lifestyle program compared with usual care (in the first, second and third echelon) on the physical activity level of COPD patients. 150 COPD patients (GOLD I-IV) will be included, aged between 40 and 80 years. In each echelon 25 patients will participate in a structured lifestyle program and 25 patients will be treated with usual care. In the structured lifestyle program, patients will be stimulated individually to enhance a physically active lifestyle. The primary outcome parameter is daily physical activity (steps/ day) assessed with a pedometer. According to the study protocol patients in the experimental group and the control group participate in four measurement sessions distributed over 15 months. In each assessment a physical fitness test, lung function and questionnaires are taken. Patients of the experimental group participate in five individual counseling sessions and one telephonic counseling.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
155

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Nov 2006

Longer than P75 for not_applicable

Geographic Reach
1 country

4 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2006

Completed
1.2 years until next milestone

First Submitted

Initial submission to the registry

January 31, 2008

Completed
13 days until next milestone

First Posted

Study publicly available on registry

February 13, 2008

Completed
1.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2009

Completed
1.3 years until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2010

Completed
Last Updated

March 26, 2012

Status Verified

November 1, 2010

Enrollment Period

2.8 years

First QC Date

January 31, 2008

Last Update Submit

March 23, 2012

Conditions

Keywords

COPDLifestylePedometer

Outcome Measures

Primary Outcomes (1)

  • Daily physical activity in steps counts a day

    Experimental group: assessment during first 3 months, 2 week assessment at 6 months, 9 months and 15 months. Control group: 2 weeks assessment at baseline, 3 months, 9 months and 15 months

Secondary Outcomes (7)

  • Personal characteristics

    assessment at baseline

  • Body Mass Index

    assessment at baseline, 3 months, 9 months and 15 months

  • Fat Free Mass

    assessment at baseline, 3 months, 9 months and 15 months

  • Lung function (FEV1)

    assessment at baseline, 3 months, 9 months and 15 months

  • Physical fitness (arm strength, leg strength, respiratory muscle strength, 6MWT)

    assessment at baseline, 3 months, 9 months and 15 months

  • +2 more secondary outcomes

Study Arms (2)

1

EXPERIMENTAL

5 counseling meetings of 30 min in the first 3 months. In counseling, patients will be stimulated individually to enhance a physically active lifestyle.

Behavioral: Coach, using a stepcounter with exercise counseling

2

NO INTERVENTION

daily physical activity is assessed at baseline, 3 months, 9 months and 15 months. No counseling.

Interventions

5 counseling meetings of 30 min in the first 3 months. In counseling, patients will be stimulated individually to enhance a physically active lifestyle.

Also known as: COACH
1

Eligibility Criteria

Age40 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age 40-80 years
  • COPD GOLD stage I-IV
  • Written informed consent

You may not qualify if:

  • Comorbidity, like serious cardiovascular problems, serious limitations in neuromuscular performance and exacerbations in the previous two months, which can effect the outcome of the study.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (4)

Wilhelmina Ziekenhuis

Assen, Netherlands

Location

Delfzicht ziekenhuis

Delfzijl, Netherlands

Location

University Medical Centre Groningen

Groningen, 9700 RB, Netherlands

Location

Diaconessenhuis

Meppel, Netherlands

Location

Related Publications (2)

  • Altenburg WA, ten Hacken NH, Bossenbroek L, Kerstjens HA, de Greef MH, Wempe JB. Short- and long-term effects of a physical activity counselling programme in COPD: a randomized controlled trial. Respir Med. 2015 Jan;109(1):112-21. doi: 10.1016/j.rmed.2014.10.020. Epub 2014 Nov 22.

  • Altenburg WA, Bossenbroek L, de Greef MH, Kerstjens HA, ten Hacken NH, Wempe JB. Functional and psychological variables both affect daily physical activity in COPD: a structural equations model. Respir Med. 2013 Nov;107(11):1740-7. doi: 10.1016/j.rmed.2013.06.002. Epub 2013 Jun 28.

MeSH Terms

Conditions

Pulmonary Disease, Chronic Obstructive

Condition Hierarchy (Ancestors)

Lung Diseases, ObstructiveLung DiseasesRespiratory Tract DiseasesChronic DiseaseDisease AttributesPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • Johan B Wempe, Phd, MD

    University Medical Center Groningen

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 31, 2008

First Posted

February 13, 2008

Study Start

November 1, 2006

Primary Completion

August 1, 2009

Study Completion

November 1, 2010

Last Updated

March 26, 2012

Record last verified: 2010-11

Locations