NCT00611988

Brief Summary

We are conducting a clinical research trial to determine the role of self-managed walking therapy to improve walking ability in patients with diabetes mellitus and peripheral arterial disease (PAD). PAD, commonly referred to as poor circulation in the legs, is a very common disease in patients with diabetes mellitus. For patients with PAD, there is a significant risk for poor walking ability and limb loss. One major treatment for PAD is walking therapy but the traditional methods for the delivery of this treatment have required frequent visits to a university or hospital-based site. We will address the role of self-managed walking program, to be conducted at or near the home, to improve limb function.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
145

participants targeted

Target at P75+ for phase_2

Timeline
Completed

Started Aug 2006

Typical duration for phase_2

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2006

Completed
1.5 years until next milestone

First Submitted

Initial submission to the registry

January 25, 2008

Completed
17 days until next milestone

First Posted

Study publicly available on registry

February 11, 2008

Completed
1.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2009

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2009

Completed
Last Updated

December 10, 2013

Status Verified

December 1, 2013

Enrollment Period

3.1 years

First QC Date

January 25, 2008

Last Update Submit

December 9, 2013

Conditions

Keywords

Walking therapyDiabetes mellitusPeripheral arterial disease

Outcome Measures

Primary Outcomes (1)

  • Maximal treadmill walking distance

    6 months

Study Arms (2)

1

EXPERIMENTAL

The intervention includes individual therapy, group reinforcement, and follow-up phone contact

Behavioral: Self-managed walking

2

ACTIVE COMPARATOR

Attention control group will receive routine follow-up phone calls

Other: Control group

Interventions

The intervention includes individual therapy, group reinforcement, and follow-up phone contact

Also known as: behavorial intervention
1

Attention control group will receive routine follow-up phone calls

Also known as: Attention control
2

Eligibility Criteria

Age40 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age 40 years and older
  • Diabetes mellitus
  • Peripheral arterial disease
  • Leg symptoms

You may not qualify if:

  • Myocardial infarction within 3 months of enrollment
  • Inability to walk for exercise secondary to chest pain, dyspnea, or poor balance
  • Prior major amputation

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

KU School of Medicine - Wichita

Wichita, Kansas, 67214, United States

Location

Related Publications (1)

  • Collins TC, Lunos S, Carlson T, Henderson K, Lightbourne M, Nelson B, Hodges JS. Effects of a home-based walking intervention on mobility and quality of life in people with diabetes and peripheral arterial disease: a randomized controlled trial. Diabetes Care. 2011 Oct;34(10):2174-9. doi: 10.2337/dc10-2399. Epub 2011 Aug 26.

MeSH Terms

Conditions

Peripheral Arterial DiseaseDiabetes Mellitus

Interventions

Control Groups

Condition Hierarchy (Ancestors)

AtherosclerosisArteriosclerosisArterial Occlusive DiseasesVascular DiseasesCardiovascular DiseasesPeripheral Vascular DiseasesGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System Diseases

Intervention Hierarchy (Ancestors)

Epidemiologic Research DesignEpidemiologic MethodsInvestigative TechniquesResearch DesignMethods

Study Officials

  • Tracie C Collins, MD

    University of Kansas Medical Center

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 2
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Prinicpal investigator

Study Record Dates

First Submitted

January 25, 2008

First Posted

February 11, 2008

Study Start

August 1, 2006

Primary Completion

September 1, 2009

Study Completion

September 1, 2009

Last Updated

December 10, 2013

Record last verified: 2013-12

Locations