Improving Posthospital Medication Management of Older Adults Through Health IT

NCT00611091 | Completed

• 2 other identifiers: 126031R18HS017203
• Study Type: interventional
• Target: 5,077
• Locations: 1 country
• Sites: 1

Brief Summary

The incidence of drug-induced injury is high in the ambulatory geriatric population and is increased for elders upon transition from the hospital to the ambulatory setting. In this application, we describe an effort to build on our extensive experience in medication safety and HIT-based medication management to respond to the AHRQ RFA entitled Ambulatory Safety and Quality Program: Improving Quality through Clinician Use of Health IT (RFA-HS-07-006). In this study, we propose to develop and evaluate the value of an enhanced, HIT-based transitional care intervention superimposed on the ambulatory electronic medical record (EMR) to improve the quality and safety of medication management, focusing particularly on the transition from the inpatient to the ambulatory setting for older adults with multiple comorbid conditions who are prescribed high risk medications. We propose a randomized controlled trial of a HIT-based transitional care intervention with enhanced medication and therapeutic monitoring alerts to improve the quality and safety of patient monitoring and medication management. We postulate that the efficient and coordinated delivery of actionable health information to the clinician via use of HIT in the ambulatory setting can improve medication safety for the growing geriatric population. The specific aims for this study are to evaluate, among a population of older adults discharged from the hospital, the impact of an enhanced discharge information system initiated upon transition to the ambulatory setting: (1) on the rate of follow-up by an outpatient provider within 14 days of hospital discharge; (2) on the prevalence of appropriate monitoring for selected high risk medications at 30 days from the time of hospital discharge; (3) on the incidence of adverse drug events (ADEs) 30 days after discharge; and (4) on the rate of emergency department visits and hospital readmission within 30 days of discharge. A secondary aim for this study is to determine costs directly related to the development and installation of the HIT-based transitional care intervention. This research allows for the examination of an integrated HIT intervention on the quality of follow-up, outpatient clinician workflow, occurrence of ADEs, and health care utilization to gain insights into the effective use of clinical alerts and coordinated delivery of actionable information to outpatient clinicians in the management of ambulatory elderly patients subsequent to hospital discharge.

Conditions

Adverse Outcomes Post-hospital Discharge

Outcome Measures

Primary Outcomes (4)

• rate of follow-up to an outpatient provider within 14 days of hospital discharge.

  1 year 3 months

• prevalence of appropriate monitoring for selected high risk medications at 30 days from the time of hospital discharge.

  1 year 3 months

• incidence of adverse drug events (ADEs) 45 days after discharge.

  1 year 3 months

• rate of hospital readmission and emergency department (ED) within 30 days of discharge.

  1 year 3 months

Secondary Outcomes (2)

• assess whether a HIT-based transitional care intervention is more effective in subgroups of patients (by level of comorbidity, number of medications, and use of specific high risk medications)

  1 year 3 months

• determine costs directly related to the development and installation of the HIT-based transitional care intervention.

  3 years

Study Arms (2)

I

EXPERIMENTAL

Intervention Group - (receive intervention) randomized at patient level - includes all health plan members, aged 65+, hospitalized at the study site hospital and discharged to an outpatient health plan clinic provider.

Other: Electronic delivery of enhanced discharge information to the ambulatory physician

C

NO INTERVENTION

Control Group - (do not receive intervention) randomized at patient level - includes all health plan members, aged 65+, hospitalized at the study site hospital and discharged to an outpatient health plan clinic provider.

Interventions

Electronic delivery of enhanced discharge information to the ambulatory physician OTHER

Follow-up appointment needs/plans

Also known as: HIT

I

Eligibility Criteria

• Age: 65 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Older Adult (65+)

You may qualify if:

• + years old, member of the study site health plan, hospitalized at the study site hospital, discharged to an outpatient provider at the study site health plan clinic

Sponsors & Collaborators

• University of Massachusetts, Worcester: lead
• Fallon Clinic: collaborator
• Agency for Healthcare Research and Quality (AHRQ): collaborator

Study Sites (1)

St Vincent's Hospital

Worcester, Massachusetts, 01608, United States

Location

Study Officials

• Jerry H Gurwitz, MD

  Meyers Primary Care Institute/University of Massachusetts Medical School

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Chief, Division of Geriatric Medicine

Study Record Dates

• First Submitted: January 25, 2008
• First Posted: February 8, 2008
• Study Start: August 1, 2010
• Primary Completion: June 1, 2012
• Study Completion: September 1, 2013
• Last Updated: September 16, 2013

Record last verified: 2013-09

Locations

US (1)