Practice Structure on Motor Learning in Post-Stroke Patients

NCT00604747 | Completed DMC

• 1 other identifier: 0038.0.254.000-05
• Study Type: interventional
• Target: 34
• Locations: 1 country
• Sites: 1

Brief Summary

Background: The literature indicates that, in relation to motor learning, healthy subjects benefit more from random practice than from constant practice. However, this effect is not well known in post-stroke patients. Objective: The goal of this study was to investigate the effects of practice structure on motor learning in post-stroke patients. Methods: Participants included an experimental group (EG) of post-stroke patients: 17 males and females; and a control group (CG) of healthy individuals: 17 males and females. At the acquisition phase, all participants performed 30 trials of a coincident timing task. Nine individuals from each group practiced constantly (C) at a stimulus propagation speed of 3 mph, and eight from each group practiced randomly (R) at speeds of 2, 3, and 5 mph. Subsequent phases included: 1) transfer, 2) retention after 15 minutes, and 3) retention after 3 days. Each of these phases included 20 trials: 10 at a speed of 1 mph, and 10 at a speed of 4 mph. Intra- and inter-group comparisons were made employing an alpha level of 0.05 (5%).

Conditions

Stroke

Keywords

motor learning; hemiplegia; stroke; practice; physiotherapy

Outcome Measures

Primary Outcomes (1)

• change in performance during the acquisition; performance exhibited during the transfer phase was maintained during retention phases 1 and 2; and differences between the groups during the transfer phase and retention phases

  time in miliseconds

Study Arms (1)

1, 2

OTHER

Other: Structure practice

Interventions

Structure practice OTHER

there were 2 groups which received random practice and constant practice during acquisition phase

Also known as: experimental group (EG), control group (CG)

1, 2

Eligibility Criteria

• Age: 40 Years - 62 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• First cerebrovascular accident
• Lesion covering the middle and the anterior cerebral artery territories
• Presence of hemiplegia or hemiparesis
• Mini-Mental State Examination (MMSE) score above 24 (19)
• Sufficient attention and comprehension to perform the task
• Absence of other associated neurological diseases.

You may not qualify if:

• Acute medical problems
• Uncorrected vision loss
• Previous history of psychiatric admission
• History of multiple strokes, transient ischemic attacks
• Pathology of the less affected, ipsilateral to stroke upper extremity that would affect ability to perform the task
• Score of 23 or less on the MMSE
• Difficulty in comprehension of verbal command and simple instructions
• Aphasia of comprehension.

Sponsors & Collaborators

• University of Sao Paulo: lead

Study Sites (1)

Camila Torriani

São Paulo, São Paulo, 02415000, Brazil

Location

MeSH Terms

Conditions

Stroke; Hemiplegia

Interventions

Control Groups

Condition Hierarchy (Ancestors)

Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases; Paralysis; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Epidemiologic Research Design; Epidemiologic Methods; Investigative Techniques; Research Design; Methods

Study Officials

• Camila Torriani

  University of Sao Paulo

  PRINCIPAL INVESTIGATOR

• Camila Torriani

  University of Sao Paulo

  STUDY CHAIR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: January 17, 2008
• First Posted: January 30, 2008
• Study Start: August 1, 2006
• Primary Completion: July 1, 2007
• Study Completion: July 1, 2007
• Last Updated: January 30, 2008

Record last verified: 2008-01

Locations

BR (1)