Effects of Lumbosacral Joint Mobilization/Manipulation on Lower Extremity Muscle Neuromuscular Response

NCT00601341 | Terminated

• 1 other identifier: 11730
• Study Type: interventional
• Target: 106
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to gain a better understanding of the effects of lumbopelvic manual therapy on lower extremity biomechanics and arthrogenic muscle response. As a result of this study, we also hope that physical therapists, athletic trainers, and other physical medicine rehabilitation providers will gain a better understanding of lower extremity injuries and have the scientific evidence to provide patients with techniques which would allow for efficient return to activities of daily living without restrictions and possibly prevent future injuries and minimize risk of osteoarthritis. The objectives of this study are to:

• Determine the amount and duration of arthrogenic muscle response of quadriceps muscles following lumbopelvic joint manipulation.
• Determine the effects of lumbopelvic joint manipulation on temporospatial parameters of gait such cadence, step length, velocity and mean peak lower extremity joint moments.
• Determine if a correlation exists between patellofemoral joint pain and lumbopelvic joint dysfunction.
• Determine the amount of change in clinical outcome measure scores following lumbopelvic joint manipulation.

Conditions

Knee Pain; Hip Pain; Ankle Pain; Lumbopelvic Pain

Keywords

arthralgia; joint pain; knee injuries; knee joint; low back pain

Outcome Measures

Primary Outcomes (1)

• Neuromuscular response (central activation ratio), characteristics of gait (stride length, step length, etc.), joint moments

  All study visits up to day 21

Secondary Outcomes (2)

• Characteristics of gait (stride length, step length, etc.)

  All study visits up to day 21

• Orthopedic special tests and questionnaires

  Concluding at day 21

Study Arms (3)

1

EXPERIMENTAL

lumbosacral joint manipulation

Other: lumbosacral joint manipulation

2

EXPERIMENTAL

lumbar passive range of motion

Other: lumbar passive range of motion

3

OTHER

lie on exam table for 3 minutes

Other: No active intervention

Interventions

lumbosacral joint manipulation OTHER

lumbosacral joint manipulation

1

lumbar passive range of motion OTHER

lumbar passive range of motion

2

No active intervention OTHER

Lie on exam table for 3 minutes

3

Eligibility Criteria

• Age: 18 Years - 50 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Physician referral to physical therapy for treatment of insidious onset of lumbopelvic or lower extremity musculoskeletal dysfunction or individuals with chronic lumbopelvic or lower extremity musculoskeletal dysfunction not wishing to seek physical therapy services.
• Unilateral or Bilateral hip pain or dysfunction
• Unilateral or Bilateral knee pain or dysfunction with two of the following symptoms:
• Pain reproduced with patella compression, squatting, prolonged sitting, going up or down stairs, or isometric quadriceps contraction.
• Unilateral or Bilateral ankle pain or dysfunction
• Lumbopelvic pain or dysfunction
• Control subjects who volunteer in response to advertisements will have healthy, pain free, back, hips, knees, and ankles.

You may not qualify if:

• Participants who are outside of age range (to ensure bony maturity while reducing the prevalence of age related degenerative changes and hypomobility.)
• Ligamentous insufficiency, meniscus damage, patellar tendonitis, history of subluxation/dislocation
• Participants with signs indicating nerve root compression (contraindication for lumbopelvic joint manipulation)
• Pain extending below knee
• Positive Straight Leg Raise
• Decreased lower extremity manual muscle test (Below 4/5), decreased sensation, hyporeflexia
• Participants demonstrating upper motor neuron signs (contraindication to lumbopelvic manipulation)
• Hyperreflexia
• Pathological reflexes
• Participants who have had lower extremity or spine surgery
• Participants who are unable to run for 5 minutes.
• Participants with ankylosing spondylitis (contraindication for lumbopelvic manipulation)
• Participants with spinal hypermobility or spondylolisthesis. (contraindication for lumbopelvic manipulation)
• Participants with spinal cord disease or cauda equina. (contraindication for lumbopelvic manipulation)
• Participants with osteoporosis. (contraindication for lumbopelvic joint manipulation)

Sponsors & Collaborators

• University of Virginia: lead
• National Athletic Trainers' Association Research & Education Foundation (NATA Foundation): collaborator

Study Sites (1)

University of Virginia

Charlottesville, Virginia, 22908, United States

Location

MeSH Terms

Conditions

Arthralgia; Knee Injuries; Low Back Pain

Condition Hierarchy (Ancestors)

Joint Diseases; Musculoskeletal Diseases; Pain; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Leg Injuries; Wounds and Injuries; Back Pain

Study Officials

• Christopher Ingersoll, PhD

  University of Virginia

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: January 14, 2008
• First Posted: January 28, 2008
• Study Start: May 1, 2005
• Primary Completion: May 1, 2009
• Study Completion: November 1, 2009
• Last Updated: June 24, 2010

Record last verified: 2010-06

Locations

US (1)