NCT00597324

Brief Summary

The study will evaluate the feasibility and safety of radial approach in patients undergoing coronary catheterisation without any restrictions based on the results of Allen's test.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
203

participants targeted

Target at P25-P50 for phase_3 coronary-artery-disease

Timeline
Completed

Started Oct 2007

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2007

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

December 26, 2007

Completed
23 days until next milestone

First Posted

Study publicly available on registry

January 18, 2008

Completed
1.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2009

Completed
1.2 years until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2010

Completed
Last Updated

October 27, 2011

Status Verified

October 1, 2011

Enrollment Period

1.7 years

First QC Date

December 26, 2007

Last Update Submit

October 26, 2011

Conditions

Keywords

Allen's testlactatesafetyradial interventionPatients with coronary artery disease

Outcome Measures

Primary Outcomes (1)

  • elevation of thumb capillary lactate after the procedure

    30 days

Secondary Outcomes (1)

  • local discomfort, disability of the instrumented arm defined as perceived (subjective) or objective muscular weakness, need for surgical intervention or RA occlusion at any time within 30 days after catheterisation.

    30 days

Study Arms (3)

1

ACTIVE COMPARATOR

Patients with normal Allen's test

Procedure: coronary catheterisation

2

EXPERIMENTAL

Patients with intermediate Allen's test

Procedure: coronary catheterisation

3

EXPERIMENTAL

Patients with abnormal Allen's test

Procedure: coronary catheterisation

Interventions

Coronary angiography which may be followed by ad hoc percutaneous intervention if indicated clinically

Also known as: Coronary angiography, PCI
123

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • All patients undergoing coronary catheterisation through radial artery

You may not qualify if:

  • Presence of haemodynamic instability
  • Planned IABP insertion
  • Previous trauma or surgical intervention in the instrumented arm
  • Impossibility to obtain informed consent

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University Hospital

Ferrara, FE, 44100, Italy

Location

Related Publications (1)

  • Valgimigli M, Campo G, Penzo C, Tebaldi M, Biscaglia S, Ferrari R; RADAR Investigators. Transradial coronary catheterization and intervention across the whole spectrum of Allen test results. J Am Coll Cardiol. 2014 May 13;63(18):1833-41. doi: 10.1016/j.jacc.2013.12.043. Epub 2014 Feb 26.

MeSH Terms

Conditions

Coronary Artery Disease

Condition Hierarchy (Ancestors)

Coronary DiseaseMyocardial IschemiaHeart DiseasesCardiovascular DiseasesArteriosclerosisArterial Occlusive DiseasesVascular Diseases

Study Officials

  • Marco Valgimigli, MD, PhD

    Azienda Universitaria Ospedaliera di Ferrara, corso Giovecca 203; 44100; Ferrara; Italy

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 3
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Head of the Catheterization laboratory

Study Record Dates

First Submitted

December 26, 2007

First Posted

January 18, 2008

Study Start

October 1, 2007

Primary Completion

June 1, 2009

Study Completion

August 1, 2010

Last Updated

October 27, 2011

Record last verified: 2011-10

Locations