Incidence of Rhabdomyolysis Among Patients Admitted With Jimsonweed Ingestions
1 other identifier
observational
46
1 country
1
Brief Summary
Retrospective chart review to determine the presence of rhabdomyolysis among patients admitted to CHMCA from 1997-2007 with Jimsonweed ingestions and to define possible risk factors predisposing patients to the developement of Jimsonweed-associated rhabdomyolysis.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for all trials
Started Jan 2008
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
January 1, 2008
CompletedStudy Start
First participant enrolled
January 1, 2008
CompletedFirst Posted
Study publicly available on registry
January 14, 2008
CompletedPrimary Completion
Last participant's last visit for primary outcome
April 1, 2008
CompletedStudy Completion
Last participant's last visit for all outcomes
April 1, 2008
CompletedJuly 28, 2008
July 1, 2008
3 months
January 1, 2008
July 25, 2008
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
The presence of rhabdomyolysis based on serum CK concentrations in patients admitted with history of Jimsonweed ingestion.
From admission until discharge
Secondary Outcomes (1)
Renal function, liver function, vital signs, physical exam
From admission until discharge
Study Arms (2)
1
Patients diagnosed with rhabdomyolysis and no history of jimsonweed ingestion
2
Patients diagnosed with rhabdomyolysis and history of jimsonweed ingestion
Eligibility Criteria
Patients diagnosed with rhabdomyolysis/ myoglobinuria/ hemoglobinuria (in-patient, out-patient, ER visit) at a CHMCA facility
You may qualify if:
- admitted to CHMCA between 1/1/1997 to 12/31/2007 with a qualifying ICD-9 diagnosis code for rhabdomyolysis, myoglobinuria, and hemoglobinuria (728.88, 791.2, 791.3)or other ICD-9 codes identified during the study
- between the ages of 0-21 years at diagnosis
You may not qualify if:
- rhabdomyolysis or serum CK concentrations not actually documented
- patient admitted to the burn center
- patient \> 21 years of age
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Children's Hospital Medical Center of Akron
Akron, Ohio, 44308, United States
Related Publications (3)
Forrester MB. Jimsonweed (Datura stramonium) exposures in Texas, 1998-2004. J Toxicol Environ Health A. 2006 Oct;69(19):1757-62. doi: 10.1080/15287390600631284.
PMID: 16905506BACKGROUNDErtekin V, Selimoglu MA, Altinkaynak S. A combination of unusual presentations of Datura stramonium intoxication in a child: rhabdomyolysis and fulminant hepatitius. J Emerg Med. 2005 Feb;28(2):227-8. doi: 10.1016/j.jemermed.2004.11.006. No abstract available.
PMID: 15707824BACKGROUNDGiannoglou GD, Chatzizisis YS, Misirli G. The syndrome of rhabdomyolysis: Pathophysiology and diagnosis. Eur J Intern Med. 2007 Mar;18(2):90-100. doi: 10.1016/j.ejim.2006.09.020.
PMID: 17338959BACKGROUND
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Martha Blackford
CHMCA
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
January 1, 2008
First Posted
January 14, 2008
Study Start
January 1, 2008
Primary Completion
April 1, 2008
Study Completion
April 1, 2008
Last Updated
July 28, 2008
Record last verified: 2008-07