Study Stopped
key study staff left foundation
The Use of CT to Identify Damaged Heart Muscle in Patients Undergoing Ventricular Tachycardia Ablation.
Utility of Delayed-Enhancement Multi-Detector Computed Tomography Imaging in Identifying Arrhymogenic Substrate in Patients Undergoing Catheter Ablation for Ventricular Tachycardia
1 other identifier
observational
4
1 country
1
Brief Summary
Patients with ventricular tachycardia (VT) undergo catheter ablation. During the ablation procedure, the heart is mapped to determine areas of heart muscle damage. The heart scarring areas are often the source of the VT. Delayed enhancement CT has recently been used to determine areas of scarring . This study is to determine if the areas of damaged heart muscle mapped with the delayed enhancement CT correlate with the same areas that are determined during the catheter ablation.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for all trials
Started Nov 2006
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
November 1, 2006
CompletedFirst Submitted
Initial submission to the registry
December 20, 2007
CompletedFirst Posted
Study publicly available on registry
December 31, 2007
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 1, 2008
CompletedStudy Completion
Last participant's last visit for all outcomes
March 1, 2008
CompletedJanuary 20, 2017
January 1, 2017
1.3 years
December 20, 2007
January 19, 2017
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Areas of hyperenhanced myocardium, as determined by delayed enhancement CT, correlate with the findings on voltage mapping of the LV in patients with a prior myocardial infarction who are undergoing VT ablation.
1 week
Eligibility Criteria
Patients coming to Cleveland Clinic for catheter ablation for ventricular tachycardia
You may qualify if:
- Age \> 21 years
- Prior myocardial infarction
- Scheduled for CT scan \< 1 week prior to VT ablation for ventricular arrythmia
You may not qualify if:
- Serum creatinine \> 1.8 mg/dL
- Contrast dye allergy
- Atrial fibrillation
- Unable to lie flat for the duration of image acquistion (15-20 minutes)
- Clinical instability at time of CT study acquisition
- Women of childbearing potential
- Personal or social problems that might prevent compliance with the study
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Cleveland Clinic
Cleveland, Ohio, 44195, United States
Related Publications (1)
Kim RJ, Fieno DS, Parrish TB, Harris K, Chen EL, Simonetti O, Bundy J, Finn JP, Klocke FJ, Judd RM. Relationship of MRI delayed contrast enhancement to irreversible injury, infarct age, and contractile function. Circulation. 1999 Nov 9;100(19):1992-2002. doi: 10.1161/01.cir.100.19.1992.
PMID: 10556226BACKGROUND
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Srikanth Sola
The Cleveland Clinic
Study Design
- Study Type
- observational
- Observational Model
- CASE ONLY
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
December 20, 2007
First Posted
December 31, 2007
Study Start
November 1, 2006
Primary Completion
March 1, 2008
Study Completion
March 1, 2008
Last Updated
January 20, 2017
Record last verified: 2017-01
Data Sharing
- IPD Sharing
- Will not share