NCT00582959

Brief Summary

The purpose of this study is to test a new technology for obtaining x-ray images of your treatment fields when you are positioned on the treatment machine, to determine whether this new system is as reliable and easy to use as conventional systems.. These so-called portal images are normally taken on a weekly basis, prior to your radiation treatment. The new portal imaging system to be tested is designed to produce better quality images than are currently achievable, but with no additional dose or added treatment time.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
19

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Apr 2004

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2004

Completed
3.7 years until next milestone

First Submitted

Initial submission to the registry

December 20, 2007

Completed
8 days until next milestone

First Posted

Study publicly available on registry

December 28, 2007

Completed
6.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2014

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2014

Completed
Last Updated

February 6, 2014

Status Verified

February 1, 2014

Enrollment Period

9.8 years

First QC Date

December 20, 2007

Last Update Submit

February 5, 2014

Conditions

Radiation Treatment for Tumors

Keywords

radiology imagingmalignancyundergoing radiation therapy

Outcome Measures

Primary Outcomes (1)

  • Obtain multiple (1-5) 3DCBIs on patients during the course of their radiation therapy treatments using a prototype megavoltage (MV) system and determine if the prototype imaging system is reliable and practical for routine clinical portal imaging.

    conclusion of the study

Secondary Outcomes (2)

  • For some patients, in addition to obtaining 1-5 MV conebeam scans, obtain 1-2 conebeam scans using a new kilovoltage conebeam imaging system

    conclusion of the study

  • Compare the quality and utility of the MV and kV conebeam systems.

    conclusion of the study

Study Arms (1)

1

OTHER

Prototype, third generation EPID based portal imaging system utilizing the MV approach.

Other: Cone Beam Imaging

Interventions

Cone Beam ImagingOTHER

Prototype, third generation EPID based portal imaging system utilizing the MV approach.

1

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Patients must have histologic proof of a malignancy suitable for radiation therapy in order to be eligible for this study

You may not qualify if:

  • None

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Memorial Sloan Kettering Cancer Center

New York, New York, 10065, United States

Location

Related Links

MeSH Terms

Conditions

Neoplasms

Study Officials

  • Michael Zelefsky, MD

    Memorial Sloan Kettering Cancer Center

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
DIAGNOSTIC
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 20, 2007

First Posted

December 28, 2007

Study Start

April 1, 2004

Primary Completion

February 1, 2014

Study Completion

February 1, 2014

Last Updated

February 6, 2014

Record last verified: 2014-02

Locations

US(1)