NCT00582101

Brief Summary

The proposed project will develop and test an HIV prevention intervention for Latino families. This study will:

  1. 1.Conduct a pilot "run-through" of an adapted family-based intervention with three cohorts (about 24 families) to determine the feasibility, acceptability, and appropriateness for the target population.
  2. 2.Revise the family-based HIV prevention intervention based on the results of the pilot "run-through" and structured exit interviews.
  3. 3.Recruit and randomize 100 families into the Latino family-based HIV prevention intervention or a general health promotion condition.
  4. 4.Estimate the effect size of the Latino family-based HIV prevention intervention from assessment of changes in HIV-related sexual behavior and attitudes and parental monitoring/supervision over 6 months.
  5. 5.The revised intervention will be feasible, acceptable, and appropriate for Latino families and will be enthusiastically received.
  6. 6.The family-based HIV prevention intervention will result in safer adolescent sexual behavior, greater change with regard to primary outcome measures of behavior (recent sexual activity, the number of unprotected sex acts, proportion of condom use, and intentions to use condoms), safer HIV-related attitudes, improved parent-child communication skills, and greater parental monitoring than the Latino families in the general health promotion condition.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
80

participants targeted

Target at P75+ for phase_1 hiv-infections

Timeline
Completed

Started May 2007

Typical duration for phase_1 hiv-infections

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 2007

Completed
8 months until next milestone

First Submitted

Initial submission to the registry

December 19, 2007

Completed
9 days until next milestone

First Posted

Study publicly available on registry

December 28, 2007

Completed
2.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2010

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2010

Completed
Last Updated

June 6, 2012

Status Verified

June 1, 2012

Enrollment Period

3.3 years

First QC Date

December 19, 2007

Last Update Submit

June 5, 2012

Conditions

Keywords

HIVpreventionfamiliesLatinoscommunicationsexualitymonitoringhealth promotionHIV PreventionHIV Seronegativity

Outcome Measures

Primary Outcomes (1)

  • Number (#) of unprotected sex acts

    baseline, 3, and 6 months

Secondary Outcomes (1)

  • parent-child communication

    baseline, 3, and 6 months

Study Arms (2)

Family-based HIV

EXPERIMENTAL
Behavioral: Family-Based HIV Prevention for Latinos

Family-based HP

ACTIVE COMPARATOR
Behavioral: General Health Promotion

Interventions

7-hour one-day workshop with adolescents and parents in separate and joint sessions

Also known as: Latino STYLE
Family-based HIV

7 hour one-day workshop on general health promotion topics

Family-based HP

Eligibility Criteria

Age13 Years - 18 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • Adolescent must be English-speaking and can converse in Spanish with parent
  • Parent must be Spanish-speaking
  • Adolescent and parent must be living together for at least 3 months prior to workshop
  • Both parent and adolescent self-identify as being of Hispanic/Latino origin

You may not qualify if:

  • Adolescent HIV positive
  • Adolescent pregnant or intending to get pregnant
  • Active psychosis

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Rhode Island Hospital

Providence, Rhode Island, 02903, United States

Location

MeSH Terms

Conditions

HIV InfectionsCommunicationSexuality

Condition Hierarchy (Ancestors)

Blood-Borne InfectionsCommunicable DiseasesInfectionsSexually Transmitted Diseases, ViralSexually Transmitted DiseasesLentivirus InfectionsRetroviridae InfectionsRNA Virus InfectionsVirus DiseasesGenital DiseasesUrogenital DiseasesImmunologic Deficiency SyndromesImmune System DiseasesBehaviorSexual Behavior

Study Officials

  • Celia M Lescano, PhD

    Rhode Island Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 1
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor (Research)

Study Record Dates

First Submitted

December 19, 2007

First Posted

December 28, 2007

Study Start

May 1, 2007

Primary Completion

September 1, 2010

Study Completion

September 1, 2010

Last Updated

June 6, 2012

Record last verified: 2012-06

Locations