NCT00578994

Brief Summary

The purpose of this study is to collect information on complications and survivorship of patients implanted with the Oxford™ Meniscal Unicompartmental Knee System at multiple sites in the United States.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
388

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Mar 2006

Longer than P75 for all trials

Geographic Reach
1 country

6 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2006

Completed
1.8 years until next milestone

First Submitted

Initial submission to the registry

December 19, 2007

Completed
2 days until next milestone

First Posted

Study publicly available on registry

December 21, 2007

Completed
12 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2019

Completed
1.2 years until next milestone

Study Completion

Last participant's last visit for all outcomes

March 31, 2021

Completed
Last Updated

April 21, 2021

Status Verified

April 1, 2021

Enrollment Period

13.8 years

First QC Date

December 19, 2007

Last Update Submit

April 19, 2021

Conditions

Keywords

Unicompartmental KneePartial KneeKnee arthroplasty

Outcome Measures

Primary Outcomes (1)

  • Survivorship

    Assessment of frequency of Revisions

    Annually for 9 years post-op

Secondary Outcomes (1)

  • Complications

    2 Years

Study Arms (1)

Oxford® Meniscal Unicompartmental Knee

Patients with PKA using the Oxford® Meniscal Unicompartmental Knee System

Device: Oxford® Meniscal Unicompartmental Knee System

Interventions

Oxford® Meniscal Unicompartmental Knee System is a medial, unicompartmental knee prosthesis containing three components: a femoral component, a tibial component, and a tibial meniscal bearing.

Oxford® Meniscal Unicompartmental Knee

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

A Multi-center study conducted in the United States of patients who meet the FDA approved indications for use. The Oxford Meniscal Unicompartmental Knee System is intended for use in individuals with osteoarthritis or avascular necrosis limited to the medial compartment of the knee and is intended to be implanted with bone cement.

You may qualify if:

  • Patients with one of the following diagnoses in the medial compartment of the knee: Osteoarthritis, Avascular Necrosis

You may not qualify if:

  • Patients with Rheumatoid arthritis or other forms of inflammatory joint disease
  • Patients with infection, sepsis, and osteomyelitis
  • Patients with Osteoporosis, Paget's Disease, Charcot's disease, Osteomalacia, and Severe Osteoporosis

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (6)

Barrington Orthopedic Specialissts

Schaumburg, Illinois, 60195, United States

Location

Joint Implant Surgeons

New Albany, Ohio, 43054, United States

Location

Mid-South Orthopedic Associates

Cordova, Tennessee, 38018, United States

Location

Texas Orthopedic Specialist

Bedford, Texas, 76021, United States

Location

Texas Center for Joint Replacement

Plano, Texas, 75093, United States

Location

Advanced Orthopaedic Centers

Richmond, Virginia, 23294, United States

Location

MeSH Terms

Conditions

OsteoarthritisOsteonecrosis

Condition Hierarchy (Ancestors)

ArthritisJoint DiseasesMusculoskeletal DiseasesRheumatic DiseasesBone DiseasesNecrosisPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • Kacy Arnold

    kacy.arnold@zimmerbiomet.com

    STUDY DIRECTOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 19, 2007

First Posted

December 21, 2007

Study Start

March 1, 2006

Primary Completion

December 31, 2019

Study Completion

March 31, 2021

Last Updated

April 21, 2021

Record last verified: 2021-04

Locations