Chlamydia Trachomatis Persistence in the Female Gastrointestinal Tract

NCT00578188 | Withdrawn

• 2 other identifiers: IRB # 43921ACH GL #039005
• Study Type: observational
• Target: N/A
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to determine if Chlamydial infections persist in the rectum of females who have had a sexually transmitted infection of Chlamydia.

Conditions

Chlamydia Infection

Keywords

Adolescent Health; Sexually transmitted infection; Women's Health

Study Arms (1)

RP100-400

Subjects with Chlamydia. The control group will also be identified with these numbers.

Eligibility Criteria

• Age: 11 Years - 19 Years
• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

11-19 year old females from the Arkansas Children's Hospital Adolescent Center

You may qualify if:

• years old
• Female
• Diagnosis of Chlamydia on enrollment visit
• Invitation to participate control group

You may not qualify if:

• Age out of range
• Negative Chlamydia screen (unless qualifies for control group)
• Unable to provide needed samples

Sponsors & Collaborators

• Arkansas Children's Hospital Research Institute: lead

Study Sites (1)

Arkansas Children's Hospital

Little Rock, Arkansas, 72202, United States

Location

Related Publications (5)

• Centers for Disease Control and Prevention (CDC). Chlamydia trachomatis genital infections--United States, 1995. MMWR Morb Mortal Wkly Rep. 1997 Mar 7;46(9):193-8.

  PMID: 9072679 BACKGROUND

• Dean D, Suchland RJ, Stamm WE. Evidence for long-term cervical persistence of Chlamydia trachomatis by omp1 genotyping. J Infect Dis. 2000 Sep;182(3):909-16. doi: 10.1086/315778. Epub 2000 Aug 17.

  PMID: 10950788 BACKGROUND

• Jones RB, Rabinovitch RA, Katz BP, Batteiger BE, Quinn TS, Terho P, Lapworth MA. Chlamydia trachomatis in the pharynx and rectum of heterosexual patients at risk for genital infection. Ann Intern Med. 1985 Jun;102(6):757-62. doi: 10.7326/0003-4819-102-6-757.

  PMID: 3888022 BACKGROUND

• Cotter TW, Ramsey KH, Miranpuri GS, Poulsen CE, Byrne GI. Dissemination of Chlamydia trachomatis chronic genital tract infection in gamma interferon gene knockout mice. Infect Immun. 1997 Jun;65(6):2145-52. doi: 10.1128/iai.65.6.2145-2152.1997.

  PMID: 9169744 BACKGROUND

• Igietseme JU, Portis JL, Perry LL. Inflammation and clearance of Chlamydia trachomatis in enteric and nonenteric mucosae. Infect Immun. 2001 Mar;69(3):1832-40. doi: 10.1128/IAI.69.3.1832-1840.2001.

  PMID: 11179361 BACKGROUND

Related Links

• Arkansas Children's Hospital Main Page

Biospecimen

Retention: SAMPLES WITH DNA

Serum, whole blood, tissue

MeSH Terms

Conditions

Chlamydia Infections; Sexually Transmitted Diseases

Condition Hierarchy (Ancestors)

Chlamydiaceae Infections; Gram-Negative Bacterial Infections; Bacterial Infections; Bacterial Infections and Mycoses; Infections; Sexually Transmitted Diseases, Bacterial; Communicable Diseases; Genital Diseases; Urogenital Diseases; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Amy M Scurlock, MD

  Arkansas Children's Hospital Research Institute

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: December 19, 2007
• First Posted: December 21, 2007
• Study Start: February 1, 2006
• Primary Completion: January 1, 2008
• Study Completion: January 1, 2008
• Last Updated: April 13, 2016

Record last verified: 2016-04

Locations

US (1)