Diagnosis of Hemangiomas and Vascular Malformations

NCT00577213 | Completed DMC

• 2 other identifiers: 47573Chancellor's Fund
• Study Type: observational
• Target: 56
• Locations: 0 countries
• Sites: N/A

Brief Summary

To develop a non-invasive, simple and affordable, measurement technique to differentiate hemangiomas from subtypes of VMS. The purpose of this study is to determine the best office based diagnositc instrument for differentiating the subtype of vascular lesions. The instrument must be simple and affordable so it can be used by primary car physicians in the doctor office. The procedure will be based on non-invasive and unharmful measurements that will be compared to the diagnosis from specialized physicians in this field and the final pathology.

Conditions

Hemangiomas; Vascular Malformations; Venular Malformations; Venous Malformations; Lymphatic Malformations; Arteriovenous Malformations

Keywords

Diagnosis; Hemangiomas; Vascular Malformations; Venular Malformations; Venous Malformations; Lymphatic Malformations; Arteriovenous Malformations

Eligibility Criteria

• Age: Up to 75 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Subjects with vascular lesions from the patient populations at Arkansas Children's Hospital (ACH) and the University of Arkansas for Medical Sciences (UAMS) will be recruited for the study. Approximately 45 subjects from Arkansas Children's Hospital and approximately 10 subjects from the University of Arkansas for Medical Sciences will be recruited for a total of 55.

You may qualify if:

• Suspected Hemangioma, Vascular Malformations (VMS) including venular Malformations (port-wine stain, PWS), Venous Malformations, Lymphatic Malformations, Arteriovenous Malformations or mixed malformations.

You may not qualify if:

• All pregnant individuals will be excluded, since physiologic changes of pregnancy could alter characteristics of the vascular lesion.

Sponsors & Collaborators

• University of Arkansas: lead

MeSH Terms

Conditions

Hemangioma; Vascular Malformations; Lymphatic Abnormalities; Arteriovenous Malformations; Disease

Condition Hierarchy (Ancestors)

Neoplasms, Vascular Tissue; Neoplasms by Histologic Type; Neoplasms; Cardiovascular Abnormalities; Cardiovascular Diseases; Congenital Abnormalities; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Lymphatic Diseases; Hemic and Lymphatic Diseases; Vascular Diseases; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Gal Shafirstein, Ph.D.

  UAMS, ACH, Central Arkansas Veterans Healthcare System

  PRINCIPAL INVESTIGATOR

• Jessica L Boswell

  UAMS, ACH, Central Arkansas Veterans Healthcare System

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: December 18, 2007
• First Posted: December 20, 2007
• Study Start: February 1, 2007
• Primary Completion: October 1, 2012
• Study Completion: October 1, 2012
• Last Updated: October 26, 2012

Record last verified: 2012-10