Magnetocardiography (MCG) in Subjects Undergoing CT Angiography (CTA)

NCT00574561 | Withdrawn

• 1 other identifier: 10057
• Study Type: observational
• Target: 300
• Locations: 1 country
• Sites: 1

Brief Summary

The investigators wish to study the magnetic field map using magnetocardiography (MCG) in subjects undergoing computed tomographic angiography (visualization of the heart arteries using CT scanning, CTA). The main purposes is to investigate if MCG is capable of detecting the presence of obstructive coronary artery disease (CAD) as detected by CT angiography (CTA) as well if the MCG can exclude the presence of CAD as defined by CTA. Secondarily the investigators will look at the correlation of MCG with non-obstructive CAD and the correlation of MCG with other tests (treadmill testing, stress echo or nuclear scan, coronary angiography) done as part of the work up for CAD.

Conditions

Chest Pain

Keywords

CT angiography (CTA); Magnetocardiography (MCG); heart disease

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients undergoing CT angiography to evaluate their coronary arteries for the presece of heart disease.

You may qualify if:

• Subjects undergoing 64-slice CT angiography

You may not qualify if:

• Hemodynamically unstable patients
• Patients with pacemakers or internal defibrillators
• Minors \< 18 years of age
• Patients unable to lie flat for the examination

Sponsors & Collaborators

• Cedars-Sinai Medical Center: lead
• CardioMag Imaging: collaborator

Study Sites (1)

Cedars-Sinai Medical Center

Los Angeles, California, 90048, United States

Location

Related Publications (6)

• 1)Stroink G, MacAuley C, Montague TJ, Horacek BM. Normal and abnormal components in magnetocardiographic maps of a subject with myocardial infarction. Med. Biol. Eng. Comp. 1985, 23, 61-62.

  BACKGROUND

• Koch H. Recent advances in magnetocardiography. J Electrocardiol. 2004;37 Suppl:117-22. doi: 10.1016/j.jelectrocard.2004.08.035.

  PMID: 15534820 BACKGROUND

• Fenici R, Brisinda D, Meloni AM. Clinical application of magnetocardiography. Expert Rev Mol Diagn. 2005 May;5(3):291-313. doi: 10.1586/14737159.5.3.291.

  PMID: 15934809 BACKGROUND

• 4)Tolstrup K, Madsen B, et al. Resting Magnetocardiography Accurately Detects Myocardial Ischemia in Chest Pain Patients with normal or non-specific ECG Findings. Cardiology. 2006;106:270-276.

  BACKGROUND

• 5)Kirsten Tolstrup, Donatella Brisinda, Anna M. Meloni, Brian Cheung, Sean Rashti, Robert J. Siegel, Riccardo Fenici. Resting Magnetocardiography is Highly Accurate for the Detection of Ischemia in Patients with Acute Chest Pain Syndrome. Submitted.

  BACKGROUND

• Stein PD, Beemath A, Kayali F, Skaf E, Sanchez J, Olson RE. Multidetector computed tomography for the diagnosis of coronary artery disease: a systematic review. Am J Med. 2006 Mar;119(3):203-16. doi: 10.1016/j.amjmed.2005.06.071.

  PMID: 16490463 BACKGROUND

MeSH Terms

Conditions

Chest Pain; Heart Diseases

Condition Hierarchy (Ancestors)

Pain; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases

Study Officials

• Kirsten Tolstrup, MD

  Cedars-Sinai Medical Center

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: December 14, 2007
• First Posted: December 17, 2007
• Study Start: July 1, 2007
• Primary Completion: December 1, 2009
• Study Completion: December 1, 2009
• Last Updated: November 17, 2009

Record last verified: 2009-11

Locations

US (1)