NCT00571792|Terminated
Study Stopped
Insufficient enrollment
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Insufficient enrollment
Sponsor study identifier
observational
42
1 country
1
Study Start
September 1, 2006
Actual (reported)Primary Completion
February 1, 2011
Actual (reported)Study Completion
February 1, 2011
Actual (reported)To explore potential proteins that may be used to develop novel therapies for COPD. This will be accomplished by acquiring material from the lower respiratory tract via endobronchial brushings.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
February 1, 2011
Actual (reported)Click on a node to explore related trials.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
September 1, 2006
Actual (reported)December 11, 2007
Actual (reported)December 12, 2007
Actual (reported)February 1, 2011
Actual (reported)February 1, 2011
Actual (reported)Imaging, genomic and proteomic methodologies to identify characteristics of individuals with normal lung function who do not smoke
Imaging, genomic and proteomic methodologies to identify characteristics of individuals who smoke but who do not demonstrate symptoms of chronic obstructive pulmonary disease
Imaging, genomic and proteomic methodologies to identify characteristics of individuals who smoke that demonstrate symptoms of COPD
Males or non-pregnant, non-nursing females who are of non-childbearing potential between the ages of 45 and 70 years of age and who may be either life long non smokers, smokers who do not demonstrate symptoms of COPD and smokers who do demonstrate symptoms of COPD
University of Nebraska Medical Center
Omaha, Nebraska, 68198-2465, United States
Genetic testing involves identification of potential proteins and biomarkers produced from the DNA and RNA analysis. Included are MMP12 and MMP9, Nrf-2 gene, heme oxygenases, glutathione, sythesizing enzymes, thioredoxin reductase, NADPH dependent quinone reductase 1 as well as certain p450 members.
Stephen I Rennard, MD
University of Nebraska
42 participants (actual enrollment reported by the registry).
First Submitted
December 11, 2007
First Posted
December 12, 2007
Study Start
September 1, 2006
Actual (reported)Study in Patients With COPD
Screening Evaluation for Studies of Chronic Obstructive Pulmonary Disease (COPD)
Contact the study team to confirm eligibility.
Primary Completion
February 1, 2011
Actual (reported)Study Completion
February 1, 2011
Actual (reported)Last Updated
December 4, 2023
Record last verified: 2023-11
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Source: ClinicalTrials.gov.
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