Alcohol and Other Psychoactive Substances in Road Traffic - a Case-control Study

NCT00570518 | Unknown

• 4 other identifiers: KTL 403-2404-3405-9406-5
• Study Type: observational
• Target: 4,500
• Locations: 1 country
• Sites: 1

Brief Summary

The main purpose of the study is to determine the accident risk when driving under the influence of psychoactive substances, including alcohol (DUI). Other aims are to find out the prevalence of psychoactive substances in road traffic and to obtain information on the role of these substances in road traffic accident causations. For the purposes of the study, drivers of motorised vehicles are randomly stopped and interviewed and breath alcohol is recorded. Also, an oral fluid sample is taken and psychoactive substances are investigated in the laboratory. For cases, drivers injured in traffic accidents are asked to participate to the study. A whole blood sample and, if possible, an oral fluid sample is taken and psychoactive substances are determined in the laboratory. Also, people diseased in road traffic accident are included in the study. The information required for these subjects are taken from a register database. The study is part of an EU-project DRUID. Altogether 13 European countries take part to the study.

Conditions

Prevalence of Psychoactive Substances in Road Traffic; Psychoactive Substances in Accident Involved Drivers; Relative Risk Estimation of Accident Involvement for Impaired Drivers

Keywords

driving under the influence; psychoactive substances; roadside surveys; hospital surveys; accident involvement risk estimation

Outcome Measures

Primary Outcomes (1)

• relative risk estimation of accident involvement for drivers impaired by psychoactive substances

  three years

Secondary Outcomes (2)

• prevalence of psychoactive substances in the general driving population

  three years

• prevalence of psychoactive substances among accident involved drivers

  three years

Study Arms (2)

1

randomly stopped drivers of motorised vehicles and bicycles

2

drivers of motorised vehicles and bicycles injured or killed in road traffic accidents

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

drivers of motorised vehicles and bicycles in general road traffic or drivers of motorised vehicles and bicycles, injured or killed in road traffic accidents

You may qualify if:

• years or older
• driver of a motorised vehicle or bicycle
• is willing to participate to the study (not applicable to the diseased drivers; information obtained from a register database)

You may not qualify if:

• or younger
• not the driver of a motorised vehicle or bicycle
• does not want to participate (not applicable to the diseased drivers; information obtained from a register database)

Sponsors & Collaborators

• Finnish Institute for Health and Welfare: lead
• Hospital District of Helsinki and Uusimaa: collaborator
• European Commission: collaborator

Study Sites (1)

National Public Health Institute

Helsinki, 00300, Finland

RECRUITING

Related Links

• The official homepage of the EU-project

Biospecimen

Retention: SAMPLES WITH DNA

Whole blood and oral fluid are collected for the study. However, no DNA determinations are done at any point of the study. The laboratory where the samples are analysed does not analyse DNA. DNA is not relevant for this study.

MeSH Terms

Conditions

Driving Under the Influence

Condition Hierarchy (Ancestors)

Criminal Behavior; Behavior; Dangerous Behavior

Study Officials

• Pirjo Lillsunde, Dr

  National Public Health Institute

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Pirjo Lillsunde, Dr

CONTACT

+358947448342; pirjo.lillsunde@ktl.fi

Charlotta Engblom, M.Sc.(Tech.)

CONTACT

+358947448546; charlotta.engblom@ktl.fi

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Sponsor Type: OTHER GOV
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: December 10, 2007
• First Posted: December 11, 2007
• Study Start: September 1, 2007
• Study Completion: October 1, 2011
• Last Updated: October 3, 2011

Record last verified: 2011-09

Locations

FI (1)