Efficacy of Escitalopram in the Treatment of Internet Addiction
2 other identifiers
interventional
31
0 countries
N/A
Brief Summary
The purpose of this study was to determine whether Lexapro (Escitalopram) is safe and effective in treating problematic internet use.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for phase_4
Started Dec 2002
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
December 1, 2002
CompletedStudy Completion
Last participant's last visit for all outcomes
October 1, 2004
CompletedFirst Submitted
Initial submission to the registry
November 28, 2007
CompletedFirst Posted
Study publicly available on registry
November 30, 2007
CompletedMay 28, 2008
May 1, 2008
November 28, 2007
May 23, 2008
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
length of non-essential Internet use in hours/week as well as CGI-Improvement
baseline and biweekly for 10 weeks
Secondary Outcomes (1)
ratings on depression, anxiety, impulsivity, self-esteem, obsessive-compulsive symptoms
baseline and biweekly for 10 weeks
Study Arms (1)
Single Arm
EXPERIMENTALEscitalopram
Interventions
Eligibility Criteria
You may qualify if:
- Subject has signed an informed consent form
- Current diagnosis of Internet addiction
- Age ³ 18
- Subject must be able to take oral medication
- Subject may be in psychotherapy initiated at least three months prior to Screening. Subject must not discontinue or otherwise alter this therapy during the study.
- In the opinion of the investigator, the subject is capable of complying with all study procedures.
You may not qualify if:
- Current suicidal or homicidal ideation
- Subject has a primary diagnosis of schizophrenia or other psychotic disorders
- Subject has a primary diagnosis of Bipolar I disorder
- Current pedophilia
- Current DSM-IV diagnosis of substance dependence or abuse, excluding nicotine
- Women of child-bearing potential who are pregnant, nursing, or not using contraception
- Use of antidepressants at a therapeutic level for the treatment of problematic internet use within 2 weeks prior to study entry (or 4 weeks for use of MAOIs, or 6 weeks for use of fluoxetine)
- Current use of antidepressants at a therapeutic level for the treatment of a disorder other than problematic internet use
- Subject has any organic mental disorder
- Clinically significant unstable medical disorder
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Icahn School of Medicine at Mount Sinailead
- Forest Laboratoriescollaborator
Related Publications (1)
Dell'Osso B, Hadley S, Allen A, Baker B, Chaplin WF, Hollander E. Escitalopram in the treatment of impulsive-compulsive internet usage disorder: an open-label trial followed by a double-blind discontinuation phase. J Clin Psychiatry. 2008 Mar;69(3):452-6. doi: 10.4088/jcp.v69n0316.
PMID: 18312057DERIVED
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Eric Hollander, MD
Icahn School of Medicine at Mount Sinai
Study Design
- Study Type
- interventional
- Phase
- phase 4
- Allocation
- NA
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
November 28, 2007
First Posted
November 30, 2007
Study Start
December 1, 2002
Study Completion
October 1, 2004
Last Updated
May 28, 2008
Record last verified: 2008-05