NCT00551993

Brief Summary

The purpose of this study is to conduct a trial of robotic assisted versus traditional laparoscopic sacrocolpopexy in the treatment of patients with vaginal prolapse.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
78

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Sep 2006

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2006

Completed
1.2 years until next milestone

First Submitted

Initial submission to the registry

October 30, 2007

Completed
2 days until next milestone

First Posted

Study publicly available on registry

November 1, 2007

Completed
4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2011

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2011

Completed
Last Updated

February 19, 2014

Status Verified

February 1, 2014

Enrollment Period

5.2 years

First QC Date

October 30, 2007

Last Update Submit

February 18, 2014

Conditions

Keywords

laparoscopyrobotvaginal prolapsesacrocolpopexysacral colpopexy

Outcome Measures

Primary Outcomes (1)

  • Primary outcome: operative time from incision to closure.

    Primary outcome: will be obtained immediately at the end of each procedure.

Secondary Outcomes (1)

  • Secondary outcomes: perioperative complications, hospital costs and post-operative patient outcomes (anatomic outcomes on physical examination and patient satisfaction using validated condition specific quality of life measures).

    Secondary outcome: will be collected over the course of the first postoperative year

Study Arms (2)

2

ACTIVE COMPARATOR

Robotic Sacral Colpopexy

Procedure: robotic laparoscopic sacrocolpopexy

1

ACTIVE COMPARATOR

Laparoscopic Sacral Colpopexy

Procedure: Laparoscopic Sacral Colpopexy

Interventions

Da Vinci Robot

2

Standard laparoscopy

1

Eligibility Criteria

Age21 Years+
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Women who are 21 years of age or greater
  • Status post hysterectomy with apical vaginal prolapse POPQ stages II-IV (prolapse from 1cm proximal to the hymen to all points distal) that desire laparoscopic surgical management.

You may not qualify if:

  • Patients that are not candidates for general anesthesia
  • Inability to consent
  • History of prior sacralcolpopexy
  • Suspicious adnexal masses or other factors that may indicate pelvic malignancy
  • History of pelvic inflammatory disease
  • Morbid obesity (body mass index greater than or equal to 40)
  • History of prior or need for concomitant rectopexy with sigmoid resection.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Cleveland Clinic

Cleveland, Ohio, 44195, United States

Location

Related Publications (1)

  • Paraiso MFR, Jelovsek JE, Frick A, Chen CCG, Barber MD. Laparoscopic compared with robotic sacrocolpopexy for vaginal prolapse: a randomized controlled trial. Obstet Gynecol. 2011 Nov;118(5):1005-1013. doi: 10.1097/AOG.0b013e318231537c.

MeSH Terms

Conditions

Pelvic Organ ProlapseUterine Prolapse

Condition Hierarchy (Ancestors)

ProlapsePathological Conditions, AnatomicalPathological Conditions, Signs and SymptomsUterine DiseasesGenital Diseases, FemaleFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesGenital Diseases

Study Officials

  • Marie Fidela M Paraiso, MD

    The Cleveland Clinic

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 30, 2007

First Posted

November 1, 2007

Study Start

September 1, 2006

Primary Completion

November 1, 2011

Study Completion

November 1, 2011

Last Updated

February 19, 2014

Record last verified: 2014-02

Locations