Effects of Medium Chain Triglyceride Oil, Versus Olive Oil, for Weight Loss
Muffin
The Effects of a Weight Loss Diet Containing Medium Chain Triglyceride Oil, Versus Olive Oil, on Body Composition in Free-Living Adults
1 other identifier
interventional
53
1 country
1
Brief Summary
The primary aim of this research project is to determine whether the incorporation of food products containing medium chain triglyceride (MCT) oil in a weight-loss program results in a different degree of weight-loss and total and regional fat mass loss than the incorporation of extra light olive oil. The secondary goals are to test whether there are differences in in metabolic risk profile changes between the 2 diets. We hypothesize that men and women who consumed MCT oil as part of their weight loss program will lose more weight and body fat than those who consume olive oil in their weight loss diet.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started Mar 2005
Typical duration for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
March 1, 2005
CompletedStudy Completion
Last participant's last visit for all outcomes
June 1, 2007
CompletedFirst Submitted
Initial submission to the registry
September 12, 2007
CompletedFirst Posted
Study publicly available on registry
September 14, 2007
CompletedSeptember 14, 2007
September 1, 2007
September 12, 2007
September 12, 2007
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Change in body weight and fat mass, change in plasma lipid concentrations, fasting glucose and fasting insulin
16 weeks
Secondary Outcomes (1)
Change in blood pressure, change in fat-free mass
16 weeks
Study Arms (2)
1
ACTIVE COMPARATORMCT oil consumption
2
PLACEBO COMPARATOROlive oil consumption
Interventions
Weight loss study including consumption of either 22-25 g of medium chain triglyceride oil or olive oil
Eligibility Criteria
You may qualify if:
- body mass index 27-33 kg/m2
- pre-menopausal women
- weight stable for at least 6 months
- normal score on Brief Symptoms Inventory questionnaire
You may not qualify if:
- chronic disease
- weight loss treatment
- medication known to affect body weight
- unstable blood pressure, glucose, lipid levels
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
University of Alabama at Birmingham
Birmingham, Alabama, 35294, United States
Related Publications (1)
St-Onge MP, Bosarge A, Goree LL, Darnell B. Medium chain triglyceride oil consumption as part of a weight loss diet does not lead to an adverse metabolic profile when compared to olive oil. J Am Coll Nutr. 2008 Oct;27(5):547-52. doi: 10.1080/07315724.2008.10719737.
PMID: 18845704DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Marie-Pierre St-Onge, Ph.D
St. Luke's-Roosevelt Hospital Center
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- DOUBLE
- Who Masked
- PARTICIPANT, CARE PROVIDER
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
September 12, 2007
First Posted
September 14, 2007
Study Start
March 1, 2005
Study Completion
June 1, 2007
Last Updated
September 14, 2007
Record last verified: 2007-09