Sponsor study identifier
interventional
602
1 country
10
Study Start
January 2006
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
December 2008
Actual (reported)Study Completion
December 2008
Actual (reported)Periodontal disease (commonly called gum disease) is generally treated by deep cleaning of the root surfaces of the teeth. This is also called scaling and root planing. Placing a topical antibiotic into the periodontal pocket at the time of scaling and root planing may help reduce pocket depth and thus help the periodontal disease. Periocline (minocycline HCl) 2.1% gel is a topical antibiotic approved in a number of countries for this use, and is now being tested in the US.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
December 2008
Actual (reported)Click on a node to explore related trials.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
January 2006
Date type not reportedThis date has not been verified as actual or estimated.
September 11, 2007
Actual (reported)September 14, 2007
Actual (reported)December 2008
Actual (reported)December 2008
Actual (reported)May 9, 2014
Actual (reported)Change in Pocket Depth.
Average change of Pocket Depth at 9 months from baseline
baseline & 9 months
sham treatment
Placebo
Minocycline HCL 2.1%
Minocycline HCl 2.1% gel as an adjunct to scaling and root planing. Dosing is by topical delivery into gingival pockets at baseline, 2 weeks, 4 weeks, 3 months and 6 months.
scaling and root planing
University of Alabama at Birmingham
Birmingham, Alabama, 35294, United States
University of California - San Francisco
San Francisco, California, 94143, United States
University of Florida
Gainsville, Florida, 32610, United States
University of Maryland - Dental School
Baltimore, Maryland, 21201, United States
Boston University Dental School
Boston, Massachusetts, 02118, United States
University of Michigan Oral Health Research Center
Ann Arbor, Michigan, 48106, United States
University of Minnesota
Robert Genco, DDS, PhD
State University of New York at Buffalo
602 participants (actual enrollment reported by the registry).
First Submitted
September 11, 2007
First Posted
September 14, 2007
Study Start
January 2006
Date type not reportedThis date has not been verified as actual or estimated.
Effect of Probiotic Inersan and Doxycycline in Chronic Periodontitis
Contact the study team to confirm eligibility.
Minneapolis, Minnesota, 55455, United States
State University of New York at Buffalo, Dental Medicine
Buffalo, New York, 14214, United States
University of Pennsylvania Dental School
Philadelphia, Pennsylvania, 19104, United States
University of Texas Health Science Center at San Antonio
San Antonio, Texas, 78229, United States
Primary Completion
December 2008
Actual (reported)Study Completion
December 2008
Actual (reported)Last Updated
May 9, 2014
Results First Posted
May 9, 2014
Record last verified: 2014-04
Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.
Source: ClinicalTrials.gov.
JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.
Source retrieved: