Biochemical Factors for a Dry Eyed Population
GARNET
1 other identifier
observational
40
1 country
1
Brief Summary
The purpose of this study is to compare various symptoms and signs of dry-eye as well as stratify characteristics of the tear film in a group of dry-eyed individuals in comparison to a group of non-dry-eyed people. Dry-eye is a condition that significantly impacts the quality of life of the sufferer. These are people who are predominantly female and in the older age groups. Determining what characterises a person with dry-eyes is of importance to understanding the disease process.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for all trials
Started May 2007
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
May 1, 2007
CompletedFirst Submitted
Initial submission to the registry
August 29, 2007
CompletedFirst Posted
Study publicly available on registry
August 30, 2007
CompletedPrimary Completion
Last participant's last visit for primary outcome
September 1, 2007
CompletedStudy Completion
Last participant's last visit for all outcomes
September 1, 2007
CompletedFebruary 16, 2009
February 1, 2009
4 months
August 29, 2007
February 12, 2009
Conditions
Keywords
Eligibility Criteria
community sample
You may qualify if:
- Is Caucasian, and has full legal capacity to volunteer.
- Is post-menopausal, with menses ceasing more than 12 months ago.
- Has moderate or severe dry eye symptoms based on dry eye questionnaire and half of the time wants to use eye drops for dry eye symptoms (dry eye group)
- Has read, understood and signed an information consent letter.
- Is willing and able to follow instructions and maintain the appointment schedule.
- Has clear corneas and no active ocular disease.
- Has had an ocular examination in the last two years.
You may not qualify if:
- Is on hormone replacement therapy (HRT).
- Ceased menses due to autoimmune disorders, mumps, chemotherapy, pelvic irradiation or smoking.
- Has rheumatoid arthritis, diabetes, Sjogren's syndrome or any other systemic disease affecting ocular health.
- Is using any systemic or topical medications (other than eye drops for dry eye symptoms) that may affect ocular health and neuroendocrine system function.
- Has undergone corneal refractive surgery.
- Is aphakic.
- Has any active ocular disease.
- Has known sensitivity to the diagnostic pharmaceuticals to be used in the study.
- Is participating in any other type of clinical or research study.
- Is a contact lens wearer.
- Has blepharitis.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- University of Waterloolead
- Alcon Researchcollaborator
Study Sites (1)
Centre for Contact Lens Research, School of Optometry
Waterloo, Ontario, N2L3G1, Canada
Biospecimen
Tears
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Desmond Fonn, M.Optom
University of Waterloo
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
August 29, 2007
First Posted
August 30, 2007
Study Start
May 1, 2007
Primary Completion
September 1, 2007
Study Completion
September 1, 2007
Last Updated
February 16, 2009
Record last verified: 2009-02