NCT00521755

Brief Summary

The purpose of this study is to evaluate the safety and effectiveness of using Seraffix LTB system for soft tissue bonding.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
15

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Dec 2008

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 26, 2007

Completed
2 days until next milestone

First Posted

Study publicly available on registry

August 28, 2007

Completed
1.3 years until next milestone

Study Start

First participant enrolled

December 1, 2008

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2009

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2010

Completed
Last Updated

June 9, 2011

Status Verified

June 1, 2009

Enrollment Period

11 months

First QC Date

August 26, 2007

Last Update Submit

June 8, 2011

Conditions

Keywords

Laser bonding soft tissue albumin

Outcome Measures

Primary Outcomes (1)

  • Primary study endpoint will be to establish the safety of using the Seraffix System for tissue bonding and wounds closure. Safety will be established by paucity of serious adverse events and adverse events.

    3 months

Secondary Outcomes (1)

  • 1. Re-intervention: A subject is scored a success (1) if he had No Re-intervention by 3 months; otherwise he is scored a failure (0). 2. Wound dehiscence of at least 50% of wound length:

    3 months

Study Arms (1)

A

EXPERIMENTAL
Device: Seraffix LTB

Interventions

laser soldering for soft tissue wounds

A

Eligibility Criteria

Age18 Years - 60 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Male/Female age 18-60.
  • Subject is scheduled for laparoscopic cholecystectomy surgery.
  • Subject able to comprehend and give informed consent for participation in this study.
  • Signed informed consent form.

You may not qualify if:

  • Unstable angina and/or congestive heart failure requiring hospitalization within the last 6 months prior to screening.
  • Acute infection requiring intravenous antibiotics at the time of screening.
  • Bleeding, coagulation and or clotting disorders.
  • Diabetes mellitus: IDDM or NIDDM.
  • HIV positive or any other immunosuppressive disorder.
  • Renal failure (Serum creatinine \>2.0 mg/dl).
  • Inflammatory and or allergic diseases or condition of the skin: Psoriasis, Eczema or dermatitis.
  • Any concomitant infection - viral or bacterial.
  • Drug abuse.
  • Use of steroids.
  • Infection / abscess / pain in treatment target area.
  • Pregnancy or lactating.
  • History of keloid scarring.
  • Use of aspirin or antioxidants
  • Subject is suffering extreme general weakness.
  • +4 more criteria

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Haemek Medical Center

Afula, Israel

Location

MeSH Terms

Conditions

Surgical Wound Dehiscence

Condition Hierarchy (Ancestors)

Postoperative ComplicationsPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • Ossama Hatoum, Dr.

    HaEmek Medical Center, Israel

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY

Study Record Dates

First Submitted

August 26, 2007

First Posted

August 28, 2007

Study Start

December 1, 2008

Primary Completion

November 1, 2009

Study Completion

February 1, 2010

Last Updated

June 9, 2011

Record last verified: 2009-06

Locations