NCT00521326

Brief Summary

The purpose of this study is to evaluate the feasibility of acquisition of coronary blood flow velocity signals over the whole length of the LAD with transthoracic pulsed Doppler, and to evaluate the diagnostic power of the transthoracic Doppler analysis package for detecting and estimating the degree of coronary artery stenosis. Finally we hope to optimize the currently available analysis package on the basis of the comparison of the Doppler with the angiographic stenosis results and evaluation.

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2007

Completed
23 days until next milestone

First Submitted

Initial submission to the registry

August 24, 2007

Completed
3 days until next milestone

First Posted

Study publicly available on registry

August 27, 2007

Completed
Last Updated

August 27, 2007

Status Verified

March 1, 2007

First QC Date

August 24, 2007

Last Update Submit

August 24, 2007

Conditions

Coronary Stenosis

Keywords

dopplercoronary stenosisnon-invasive testingA prospective study of a new diagnostic method.Study consists of a transthoracic doppler of LAD.Doppler to be performed prior to coronary angiography.F/U doppler examination for those who undergo PCI.Doppler results will be compared with coronary angiography.

Study Arms (1)

A

Patients with an acute coronary syndrome that are candidates for coronary angiography. Doppler results will be compared to angiographic findings.

Eligibility Criteria

Age18 Years+
Sexall
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients who are clinically suspected of having significant coronary artery stenosis.
  • Patients with CAD.
  • Patients who are scheduled to undergo coronary angiography.
  • Signed informed consent.

You may not qualify if:

  • Patients with arrhythmia / irregular pulse
  • Patients with unstable conditions: unstable angina, uncontrolled CHF
  • Patients with COPD
  • Any physical or medical disability that prevent lying in supine position
  • Patients with chest wall deformity

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Coronary Care Unit, Heart Institute, Hille Yaffe Medical Center

Hadera, 38100, Israel

Location

MeSH Terms

Conditions

Coronary Stenosis

Condition Hierarchy (Ancestors)

Coronary DiseaseMyocardial IschemiaHeart DiseasesCardiovascular DiseasesVascular Diseases

Study Officials

  • Simcha R Meisel, MD, MSc

    Hillel Yaffe Medical Center

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Simcha R Meisel, MD, MSc

CONTACT

972-4-630-4656meisel@hy.health.gov.il

Avraham Shotan, MD

CONTACT

972-4-630-4428shotana@yahoo.com

Study Design

Study Type
observational
Observational Model
DEFINED POPULATION
Time Perspective
OTHER
Sponsor Type
OTHER GOV

Study Record Dates

First Submitted

August 24, 2007

First Posted

August 27, 2007

Study Start

August 1, 2007

Last Updated

August 27, 2007

Record last verified: 2007-03

Locations

IL(1)