NCT00517374

Brief Summary

To establish a solid foundation, e.g. a network and a coordinating centre for testing new SCI therapies in forthcoming randomised controlled multi-centre clinical trials following international standards and guidelines.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
600

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Sep 2005

Typical duration for all trials

Geographic Reach
1 country

17 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2005

Completed
2 years until next milestone

First Submitted

Initial submission to the registry

August 15, 2007

Completed
1 day until next milestone

First Posted

Study publicly available on registry

August 16, 2007

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2007

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2007

Completed
Last Updated

September 25, 2015

Status Verified

September 1, 2015

Enrollment Period

2.2 years

First QC Date

August 15, 2007

Last Update Submit

September 24, 2015

Conditions

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Each study enrolled Hospital in China and Hong Kong is expected to recruit 20 chronic spinal cord injury patients, who have never had any cell therapy treatment for spinal cord injur before.

You may qualify if:

  • General
  • Male or female adult subjects, 18 to 65 years of age
  • Have a clinical diagnosis of SCI, defined by MRI
  • Voluntarily signs and dates an Informed Consent Form, approved by an Institutional Review Board (IRB)/Independent Ethics Committee (IEC), prior to any study-specific procedures
  • Acute SCI Study Group:
  • Has an acute SCI (defined as \< 7 days post-injury)
  • Chronic SCI Study Group:
  • \. Has a chronic SCI (defined as \> 12 months post-initial SCI surgery)

You may not qualify if:

  • General
  • Severe head injury
  • Is medically or mentally unstable according to the judgement of the Investigator
  • History of Multiple Sclerosis or peripheral demyelinating disease
  • Likely to have experimental therapy
  • Any criteria, which, in the opinion of the investigator, suggests that the subject would not be compliant with the study protocol

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (17)

First Affiliated Hospital of Medical College, Shantou University

Shantou, Guangdong, China

Location

Ningbo Second People Hospital

Ningbo, Zhejiang, China

Location

Beijing Army General Hospital

Beijing, China

Location

Beijing University People's Hospital

Beijing, China

Location

Beijing Xishan Hospital

Beijing, China

Location

China Rehabilitation Research Center

Beijing, China

Location

Nanfang Hospital

Guangzhou, China

Location

Second Affliliated Hospital of Sun Yat-sen University

Guangzhou, China

Location

Prince of Wales Hospital

Hong Kong, China

Location

Queen Mary Hospital

Hong Kong, China

Location

Chengdu Army Kuming General Hospital

Kunming, China

Location

Changhai Hospital

Shanghai, China

Location

Shanghai East Hospital

Shanghai, China

Location

Zhongshan Hospital

Shanghai, China

Location

Tianjin Medical University Hospital

Tianjin, China

Location

Xian Jiaotong University Second Hospital

Xi'an, China

Location

Xijing Hospital

Xi'an, China

Location

MeSH Terms

Conditions

Spinal Cord Injuries

Condition Hierarchy (Ancestors)

Spinal Cord DiseasesCentral Nervous System DiseasesNervous System DiseasesTrauma, Nervous SystemWounds and Injuries

Study Officials

  • Wise Young, MD, PhD

    Unaffilated

    STUDY DIRECTOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
NETWORK

Study Record Dates

First Submitted

August 15, 2007

First Posted

August 16, 2007

Study Start

September 1, 2005

Primary Completion

December 1, 2007

Study Completion

December 1, 2007

Last Updated

September 25, 2015

Record last verified: 2015-09

Locations